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    Restoring the blood-brain barrier? - 10 month(s) ago

    Stanford Medicine scientists and collaborators discover a treatment in mice to repair the blood-brain barrier, which is key to brain health.

    Source: Scope
    Categories: Healthcare Professionals, Latest Headlines
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      westr

      Restoring the blood-#brainbarrier? https://t.co/jghzyCSjuz “The finding shows that, in mice, the blood-#brain barrier could be restored by drugs that activate #FZD receptors and the #WNT signaling pathway.” #frizzled #BBB

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    Caltech’s Enzyme Discovery Enables New Mechanism for Crossing the Blood–Brain Barrier - 12 month(s) ago

    Caltech researchers discovered an enzyme that enables viral vectors to cross the blood-brain barrier, potentially aiding brain disorder drug development and research. The blood–brain barrier (BBB) is a stringent, nearly impenetrable layer of cells that guards the brain, protecting the vital organ

    Source: SciTechDaily
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      westr

      Caltech’s Enzyme Discovery Enables New Mechanism for Crossing the Blood–#BrainBarrier - https://t.co/ce2GGgeab4 #CNS #BBB #CAIV #CarbonicAnhydrase Primate-conserved carbonic anhydrase IV and murine-restricted #LY6C1 enable #bloodbrainbarrier crossing by engineered #viralvectors… https://t.co/V7BXP6awxu https://t.co/64xHqvXt9U

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    The association between inflammatory markers in blood and cerebrospinal fluid: a systematic review and meta-analysis - Molecular Psychiatry - 1 year(s) ago

    Neuroinflammatory processes have been hypothesized to play a role in the pathogenesis of psychiatric and neurological diseases. Studies on this topic often rely on analysis of inflammatory biomarkers in peripheral blood. Unfortunately, the extent to which these peripheral markers reflect inflammatory processes in the central nervous system (CNS) is unclear. We performed a systematic review and…

    Source: Nature
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      westr

      The association between #inflammatory markers in blood and #cerebrospinalfluid: a systematic review and meta-analysis: https://t.co/dTukRG6ISP #BBB #neuroinflammation #CSF collection is invasive! Unfortunately, however ... "The majority of studies reported no significant… https://t.co/2CN3Fa1ov2 https://t.co/fjwIcOYYkC

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    Stuck on you: Meninges cellular crosstalk in development - 1 year(s) ago

    The spatial and temporal development of the brain, overlying meninges (fibroblasts, vasculature and immune cells) and calvarium are highly coordinated…

    Source: www.sciencedirect.com
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      westr

      REVIEW: Stuck on you: #Meninges cellular crosstalk in #development. @SiegenthalerLab https://t.co/o1HQ1T2mYy #brain #duramater #Arachnoiditis #biomarkers Expeditious approach to role of #leptomeninges & #BBB in health and #neurodegeneration See also: https://t.co/vdrPDKA2qW https://t.co/JPTTEbr1Wq

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    Brain Barriers - 1 year(s) ago

    Cold Spring Harbor Meetings and Courses – Long Island, New York. Scientific Conferences and Courses For Research and Education

    Source: meetings.cshl.edu
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      westr

      Cold Spring Harbor Meetings and Courses - Long Island, New York. Scientific Conferences and Courses For Research and Education https://t.co/F3tx2LXJvu #CSF #DLM #Leptomeninges #Leptomeningitis #Meningitis #BBB #arachnoiditis @arcsology #CSH

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    Caffeine: What Is Its Role in Pain Medicine? - 2 year(s) ago

    Caffeine is the world’s most widely used psychoactive legal substance. The involvement of caffeine in pain management has gotten minimal attention in the past, but it is getting more attention now. This article provides a brief assessment of the literature to clarify the role of caffeine as a pain reliever and stimulate the interest of researchers. Caffeine affects adenosine receptors, which are…

    Source: www.cureus.com
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      westr

      #Caffeine: What Is Its Role in #PainMedicine? https://t.co/cWGe8FgJAT @CureusInc #pain #ChronicPain #Adenosine #headache #migraine #epidural #CSFleak #BBB "Caffeine can pass the blood-brain barrier and operate as a #vasoconstrictor in the cerebral vascular system."

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