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Mashup Score: 12Associations of Lifelong Exercise Characteristics With Valvular Function and Aortic Diameters in Patients With a Bicuspid Aortic Valve - PubMed - 2 month(s) ago
We found no deleterious associations between lifelong exercise characteristics, valvular dysfunction, and aortic dilatation in patients with a bicuspid aortic valve. Vigorous intensity and exercise in mixed sports were associated with a lower prevalence of moderate-to-severe aortic stenosis. These o …
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 2Balloon Aortic Valvuloplasty in the Modern Era: A Review of Outcomes, Indications, and Technical Advances - 8 month(s) ago
Balloon aortic valvuloplasty (BAV) improves the hemodynamics and symptoms of patients with severe aortic stenosis in the short term with low rates of …
Source: www.sciencedirect.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Aortic regurgitation provokes phenotypic modulation of smooth muscle cells in the normal ascending aorta - PubMed - 8 month(s) ago
AR itself negatively impacts SMC phenotype in the ascending aortic wall. This AR-specific effect is independent of aortic diameter and aortic valve morphology, although it is more pronounced with BAVs. These findings provide insight into the mechanisms of AR-related aortic remodeling, and they provi …
Source: pubmed.ncbi.nlm.nih.govCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Novel Association of the NOTCH Pathway Regulator MIB1 Gene With the Development of Bicuspid Aortic Valve - PubMed - 9 month(s) ago
This genetic association study identified the MIB1 gene as associated with nsBAV. This underscores the crucial role of the NOTCH pathway in the pathophysiology of BAV and its potential as a target for future diagnostic and therapeutic intervention.
Source: PubMedCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 3
Our results indicate that BAV and thoracic aortic disease carry a significant familial association for concordant disease and aortic dissection. The pattern of familiality is consistent with a genetic cause of disease. Furthermore, we observed higher risk of aortic-specific mortality in relatives of …
Source: PubMedCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Aortic Size at the Time of Type A and Type B Dissections - PubMed - 11 month(s) ago
Aortic diameter at the time of Type A dissection is consistent with the new guidelines which recommend surgical intervention at 5.0cm. Type B dissection occurs at small sizes and cannot be prevented using a size criterion.
Source: PubMedCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 1Natural History of Truncal Root Dilatation and Truncal Valve Regurgitation in Truncus Arteriosus - PubMed - 12 month(s) ago
Root dilatation in TA persists for up to 30 years post-repair. Patients with bicuspid and quadricuspid truncal valves demonstrated greater root dilatation over time and required more valve interventions. Continued longitudinal follow-up is warranted in this higher-risk cohort.
Source: PubMedCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 3
Background Description of cerebral and retinal infarction in patients with bicuspid aortic valve (BAV) is limited to case reports. We aimed to characterize cerebral and retinal infarction and examine outcomes in patients with BAV. Methods and Results Consecutive patients from 1975 to 2015 with BAV ( …
Source: PubMedCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 3The Natural History of Bicuspid Aortic Valve Disease - 1 year(s) ago
The bicuspid aortic valve (BAV) is the most common congenital heart defect with an estimated prevalence of between 0.5% and 2% in the United States, representing up to 6.5 million individuals. Most individuals with BAV will develop valvular and/or aortic complications related to their BAV. How these various complications relate to one another and why they arise remain elusive. Yet, astute…
Source: Structural HeartCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
Although they were significantly younger, patients with BAV who had isolated severe AS had worse preoperative LV function and an increased risk of postoperative heart failure hospitalization compared with patients who had TAV. Our findings suggest that patients who have BAV with AS might benefit fro …
Source: PubMedCategories: Cardiologists, Latest HeadlinesTweet
Super important data! Assuming self-report is correct, exercise has no association with aortic size in #BAV. Another win for regular physical activity counseling! No assessment of high impact/heavy resistance training. @SamWittekind @daniel_forsha https://t.co/Q0Mu7YnYci