-
Mashup Score: 1We wouldn't have Ozempic without Gila monsters — their hunger-regulating venom inspired weight-loss drugs - 10 month(s) ago
Ozempic was created thanks to research on Gila monsters, the only venomous lizard in the US. Their venom slows digestion and curbs cravings for hours.
Source: InsiderCategories: Cardiologists, Latest HeadlinesTweet
-
Mashup Score: 1Basic, Clinical and Translational Research: What's the Difference? | Dana-Farber Cancer Institute - 1 year(s) ago
Published: December 12, 2017Updated: November 16, 2018“Research” is a broad stroke of a word, the verbal equivalent of painting a wall instead of a masterpiece. There are important distinctions among the three principal types of medical research — basic, clinical and translational. Whereas basic research is looking at questions related to how nature works, translational … Read more
Source: Dana-Farber Cancer InstituteCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
“Research” is a broad stroke of a word, the verbal equivalent of painting a wall instead of a masterpiece. There are important distinctions among the three principal types of medical research — #basicresearch, #clinicalresearch, and #translationalresearch. https://t.co/4iyBxwlw73
-
-
Mashup Score: 0Targeting the Autophagy-Lysosome Pathway in a Pathophysiologically Relevant Murine Model of Reversible Heart Failure: - 1 year(s) ago
Highlights • The biological drivers of reverse LV remodeling are not well understood. • Transaortic constriction induced hemodynamic pressure overload superimposed on acute LAD ligation in mice res…
Categories: Expert Picks, Latest HeadlinesTweet-
What is the therapeutic relevance of enhancing autophagic flux in the heart? Find out in #JACCBTS: https://t.co/hzWzf1HmWC #HeartFailure #openaccess #BasicResearch #TranslationalScience #CardioTwitter @DLMann_MD https://t.co/zVreb67j10
-
-
Mashup Score: 1A Novel Puncturable Atrial Septal Defect Occluder: The Results of Preclinical Experiment and First-in-Human Study - 1 year(s) ago
Highlights • In the presence of an ASD occluder, the subsequent puncture of the atrial septum for such patients may be challenging, and this important route for left-sided interventional procedures…
Categories: Expert Picks, Latest HeadlinesTweet-
First-in-human study of a puncturable atrial septal defect occluder. https://t.co/pJWPv2N26t #JACCBTS #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/27sKCLQA9g
-
-
Mashup Score: 0Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction: - 1 year(s) ago
Highlights • Boosting NAD+ by NR has been shown to blunt worsening of cardiac function in murine cardiomyopathy models and suggested to have anti-inflammatory effects a small, nonrandomized clinica…
Categories: Expert Picks, Latest HeadlinesTweet-
Can nicotinamide riboside be a potential therapy for #HeartFailure patients? Learn more in #JACCBTS: https://t.co/joqtq21IRk #openaccess #BasicResearch #HFrEF #CardioTwitter https://t.co/s5w74PpMdt
-
-
Mashup Score: 2Novel GSK-3β Inhibitor Neopetroside A Protects Against Murine Myocardial Ischemia/Reperfusion Injury: - 1 year(s) ago
Highlights • Neopetroside A preserved cardiac hemodynamics and mitochondrial respiration capacity ex vivo after ischemia/reperfusion injury in rat hearts. • NPS A significantly prevented cardiac fi…
Categories: Expert Picks, Latest HeadlinesTweet-
How does neopetroside A prevent cardiac fibrosis in mouse model of myocardial infarction? Find out in #JACCBTS: https://t.co/DDDhf68aLt #openaccess #BasicResearch #TranslationalScience #cvMI #CardioTwitter https://t.co/b2mxD21kow
-
-
Mashup Score: 0Antiplatelet Effects of Clopidogrel Vs Aspirin in Virologically Controlled HIV: A Randomized Controlled Trial - 1 year(s) ago
Highlights • In treated HIV, cardiovascular disease is a leading cause of morbidity and mortality, the prevention of which is not fully known. • Activated platelets are causal in atherosclerotic ca…
Categories: Expert Picks, Latest HeadlinesTweet-
Does #clopidogrel offer beneficial antiplatelet properties in #HIV patients? Learn more in #JACCBTS: https://t.co/YxfdZcomYx #Aspirin #openaccess #BasicResearch #TranslationalResearch #CardioTwitter @plateletdoc https://t.co/bA1y5ElXI3
-
-
Mashup Score: 6Determinants of Endogenous Fibrinolysis in Whole Blood Under High Shear in Patients With Myocardial Infarction: - 1 year(s) ago
Highlights • Hypofibrinolysis is a recently-recognized risk factor for recurrent cardiovascular events in patients with STEMI, but its mechanistic determinants are not well understood. • In patient…
Categories: Expert Picks, Latest HeadlinesTweet-
Insight into bidirectional crosstalk between coagulatory and inflammatory pathways. https://t.co/Hu7e43qvDs #JACCBTS #cvMI #openaccess #BasicResearch #TranslationalResearch #CardioTwitter https://t.co/fWpw710Iu6
-
-
Mashup Score: 0LncRNA-ZFAS1 Promotes Myocardial Ischemia-Reperfusion Injury Through DNA Methylation-Mediated Notch1 Down-Regulation in Mice: - 1 year(s) ago
Highlights • The increase of ZFAS1 expression in MIRI is an important cause of cardiomyocyte apoptosis and ROS production. • ZFAS1 can directly interact with the promoter region of Notch1, recruit …
Categories: Cardiac Surgery, Latest HeadlinesTweet-
ICYMI: How does LncRNA-ZFAS1 promote myocardial ischemia reperfusion injury? Find out in #JACCBTS: https://t.co/L39qVI6iwA #IHD #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/tiKpbaDiCP
-
-
Mashup Score: 2Plasminogen Activator Inhibitor-1–Positive Platelet-Derived Extracellular Vesicles Predicts MACE and the Proinflammatory SMC Phenotype: - 1 year(s) ago
Highlights • This study shows the existence of PAI-1+ PEVs. Approximately 20% of plasma PAI-1 is composed of PAI-1+ PEVs. • Elevated PAI-1+ PEV levels were predictive of 1-year major adverse cardia…
Categories: Expert Picks, Latest HeadlinesTweet-
ICYMI: Can PAI-1+ PEV levels predict adverse cardiac events? Find out in #JACCBTS: https://t.co/GR5apM6y8l #cvCAD #openaccess #BasicResearch #TranslationalScience #CardioTwitter https://t.co/RXYepn8NVO
-
What Is Ozempic Made From? GLP-1 Drugs Developed Using Gila Monster. Curiosity-driven #BasicResearch pays off! https://t.co/72QOFiZO2r