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    Bacteria Eaters: The “Twort-d’Hérelle Phenomenon” by John Emrich and Charles Richter December 2021 Two decades after diphtheria antitoxin became a clinical success at the end of the 19th century, greatly reducing death from the disease, especially among young children, a new phenomenon with claims of vast therapeutic potential against bacterial infections burst onto the scene. The…

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    • In the early days of #bacteriophage therapy, manufacturers got a little creative with their names. Today, phage researchers get A LOT creative. https://t.co/NzQw81JVba

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    A new base editing method edits a particular bacterium within a community while the rest of the microbiome remains unchanged. The technology enables studies to better understand the genetic basis of key bacterial interactions with plants and other microbes within the context of a controlled ecosystem. The proof-of-concept study could be used to alter members in a variety of complex microbial…

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    • Editing Specific Bacteria in Soil Microbiomes Using #Phage Delivered Base Editors Scientists at @NCState have developed a method to precisely edit a single gene in a targeted bacterial species within a microbial community. Read now: https://t.co/h8YBDBG8Xs #bacteriophage #CRISPR https://t.co/Atrp4qY0UT

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    A new base editing method edits a particular bacterium within a community while the rest of the microbiome remains unchanged. The technology enables studies to better understand the genetic basis of key bacterial interactions with plants and other microbes within the context of a controlled ecosystem. The proof-of-concept study could be used to alter members in a variety of complex microbial…

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    • Editing Specific Bacteria in Soil Microbiomes Using #Phage Delivered Base Editors Scientists at @NCState have developed a method to precisely edit a single gene in a targeted bacterial species within a microbial community. Read now: https://t.co/h8YBDBXJP0 #bacteriophage #CRISPR https://t.co/eJ2FpbhEHO

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    A trial to assess bacteriophage, or “phage,” therapy, which utilizes a virus to target specific bacteria and leave behind other bacteria and human cells, is underway among patients with cystic fibrosis, according to an NIH press release.The National Institute of Allergy and Infectious Diseases (NIAID) is funding a trial conducted by the Antibacterial Resistance Leadership Group (ARLG)

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    • "We hope it is safe and to demonstrate a microbiological effect," Henry F. “Chip” Chambers, MD, from the @ARLGnetwork, said about a current clinical trial assessing #bacteriophage, or “phage,” therapy, among patients with cystic fibrosis. https://t.co/PGa2qYdAzG

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    Author summary Horizontal gene transfer is a major driver of evolution and adaptation in bacteria. Genes from outside may be beneficial or dangerous to the receiving cell. Benefits include new food sources such as sugars, or new homes by adhesion, or new resistances, as to antibiotics. Dangers are posed by bacteriophages–viruses that take over the cell machinery, multiply, and release progeny to…

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    • New research on horizontal gene transfer: Zaworski et al @NEBiolabs show the stySA RM locus of #Salmonella enterica is a variant BREX (BacteRiophage EXclusion) system @ettwiller #bacteria #bacteriophage #Genetics https://t.co/4wFwEUkUDt