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Mashup Score: 0Baclofen for the Treatment of Alcohol Use Disorder - 11 month(s) ago
Study Population: 1,818 adults with alcohol use disorder in 17 randomized controlled trials; the mean age was 46.5 years, and 70% were men
Source: www.aafp.orgCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 4DEFINE_ME - 3 year(s) ago
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Source: secure.jbs.elsevierhealth.comCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 1
Baclofen is a popular muscle relaxant that is eliminated primarily unchanged in the urine.1 We recently reported a higher risk of encephalopathy in a cohort of 15,942 older adults with chronic kidney disease (CKD) who started baclofen at≥20 versus<20mg/d; a higher risk was also observed in all baclofen users versus nonusers.2 In another study of patients receiving dialysis, 1 in 14 were...
Categories: Latest Headlines, NephrologyTweet
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Mashup Score: 1A pill to fight alcoholism causes an uproar in France - 4 year(s) ago
Two years ago, French regulators overruled one of their own expert committees to approve a controversial drug for combating alcohol use disorder.
Source: STATCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 1Baclofen Toxicity in Kidney Disease - 4 year(s) ago
Baclofen, a commonly prescribed muscle relaxant, is primarily excreted via the kidneys; toxicity is a potentially serious adverse outcome in patients with decreased kidney function. We describe a patient with end-stage kidney disease receiving hemodialysis who developed neurotoxicity and hemodynamic instability after receiving baclofen for muscle spasms. In this case, prompt recognition of…
Categories: NephrologyTweet
Baclofen is a selective agonist of gamma-aminobutyric acid receptors that was initially approved for the treatment of muscle spasticity and is now being evaluated for the treatment of alcohol use disorder. https://t.co/4MR2iNJoxt #familymedicine #baclofen