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Mashup Score: 1TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress - Nature Communications - 10 month(s) ago
Researchers reveal how the stress of the endoplasmic reticulum is transmitted to the nuclear envelope, which swells, and is brought back to physiologic shape by autophagic pathways.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 2TMX4-driven LINC complex disassembly and asymmetric autophagy of the nuclear envelope upon acute ER stress - Nature Communications - 10 month(s) ago
Researchers reveal how the stress of the endoplasmic reticulum is transmitted to the nuclear envelope, which swells, and is brought back to physiologic shape by autophagic pathways.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
Asymmetric autophagy of the nuclear envelope upon acute ER stress #SEC62 #ER-phagy #Autophagy #ONM-phagy #TMX4 #LINC complex @MolinariLab @BellinzonaIrb https://t.co/whci6ddnTr
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Mashup Score: 0Autophagy-related genes analysis reveals potential biomarkers for prediction of the impaired walking capacity of peripheral arterial disease - BMC Medicine - 11 month(s) ago
Background The role of autophagy and autophagy-related genes in peripheral arterial disease (PAD) remains unknown and may be of diagnostic and prognostic value. The aim of this study is to investigate the relationship between autophagy and PAD, and identify potential diagnostic or prognostic biomarkers for medical practice. Methods Differentially expressed autophagy-related genes in PAD were…
Source: BioMed CentralCategories: General Medicine Journals and Societies, Latest HeadlinesTweet-
#Autophagy-related genes analysis reveals potential biomarkers for predicting impaired walking capacity in patients with #PeripheralArterialDisease. https://t.co/smkaOAAi3D Dai et al link Brandenburg Medical School #chemokine #vascular #inflammation with #PAD. https://t.co/j65DIzvx1X
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Mashup Score: 0
Kimmelman and colleagues discuss the role of autophagy in tumor cells and of cell-nonautonomous autophagy in the microenvironment and host cells in supporting tumor growth and reflect on open questions in the field.
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
💫NEW REVIEW ARTICLE @NatureCancer - “Impact of context-dependent autophagy states on tumor progression” by #AlecKimmelman and #MohamadAssi. #Autophagy Read it here👇 https://t.co/lPqyCTIUBt https://t.co/RKoEFzBa1a
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Mashup Score: 0Traumatic Brain Injury Interferes with Immune System Cells’ Recycling Process in Brain Cells - 1 year(s) ago
In a new study published in the January issue of Autophagy, they found that after traumatic brain injury, the brain’s immune system cells’ internal recyclin
Source: www.newswise.comCategories: Healthcare Professionals, Latest HeadlinesTweet-
Traumatic #BrainInjury Interferes with Immune System Cells’ Recycling Process in Brain Cells https://t.co/3L73mTLXl4 #TBI #neuroinflammation #neurdegeneration #cognition Inhibition of #autophagy in #microglia and #macrophages exacerbates innate immune responses and worsens… https://t.co/bFUHZbaRsg https://t.co/6AQvk6Y6Rz
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Mashup Score: 15Autophagy and autophagy-related pathways in cancer - Nature Reviews Molecular Cell Biology - 1 year(s) ago
Autophagy can serve both tumour-suppressive and tumour-promoting roles, often depending on disease stage and mutational background. Recent findings have advanced our understanding of these seemingly opposing roles of autophagy in cancer cells themselves and in the tumour microenvironment.
Source: NatureCategories: Allergy-Immunology, Latest HeadlinesTweet-
Happy Monday! Our latest #NRMCBReview has now gone online - Debnath, Noor and Ryan discuss #autophagy and related processes in #cancer. Read their comprehensive discussion here! đź”— https://t.co/dBPGTln1Lf https://t.co/HQRwjMZ1i0
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Mashup Score: 3
Lysosomal autophagy inhibition (LAI) in cancer induces lipid remodeling that resists cell death associated with lysosomal membrane permeabilization, which can be abrogated by targeting UDP-glucose ceramide glucosyltransferase in the face of LAI.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
From the February issue— Targeting UGCG Overcomes Resistance to Lysosomal #Autophagy Inhibition, by @VaibhavJain_PhD, David Speicher, @AmaravadiRavi et al. https://t.co/vMfhg5t2oN @TheWistar @PennCancer https://t.co/NzA9kDdGY6
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Mashup Score: 0Transient Systemic Autophagy Inhibition Is Selectively and Irreversibly Deleterious to Lung Cancer - 1 year(s) ago
Transient loss of systemic autophagy causes irreversible damage to tumors by suppressing cancer cell metabolism and promoting antitumor immunity, supporting autophagy inhibition as a rational strategy for treating lung cancer.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Transient Systemic #Autophagy Inhibition Is Selectively and Irreversibly Deleterious to #LungCancer, by Khayati, @YanxiangGuo et al. https://t.co/QoKeUxZBY8 @EileenWhitePhD @vrushank_bhatt @narita_lab https://t.co/3IzcX1RDBw
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Mashup Score: 1Transient Systemic Autophagy Inhibition Is Selectively and Irreversibly Deleterious to Lung Cancer - 1 year(s) ago
Transient loss of systemic autophagy causes irreversible damage to tumors by suppressing cancer cell metabolism and promoting antitumor immunity, supporting autophagy inhibition as a rational strategy for treating lung cancer.
Categories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Transient Systemic #Autophagy Inhibition Is Selectively and Irreversibly Deleterious to #LungCancer, by Khayati, @YanxiangGuo et al. https://t.co/t7UwWmhRaH @EileenWhitePhD @vrushank_bhatt @narita_lab https://t.co/E0RPWIhpXN
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Mashup Score: 2Chronic pain causes Tau-mediated hippocampal pathology and memory deficits - Molecular Psychiatry - 1 year(s) ago
Persistent pain has been recently suggested as a risk factor for dementia. Indeed, chronic pain is frequently accompanied by maladaptive brain plasticity and cognitive deficits whose molecular underpinnings are poorly understood. Despite the emerging role of Tau as a key regulator of neuronal plasticity and pathology in diverse brain disorders, the role of Tau has never been studied in the…
Source: NatureCategories: Healthcare Professionals, Latest HeadlinesTweet-
#Chronicpain causes #Tau-mediated hippocampal pathology and #memory deficits https://t.co/In8tu0t2sE #neuropathicpain #dementia #cognition Chronic pain inhibits #autophagy in #hippocampus while the analgetic drug, #Gabapentin reverts this SNI-driven action https://t.co/AoJsktzCV3 https://t.co/7BOYBfIbft
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Asymmetric autophagy of the nuclear envelope upon acute ER stress #SEC62 #ER-phagy #Autophagy #ONM-phagy #TMX4 #LINC complex @MolinariLab @BellinzonaIrb https://t.co/whci6ddnTr