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Mashup Score: 1The Emerging Role of MAIT Cell Responses in Viral Infections - 8 month(s) ago
Abstract. Mucosal-associated invariant T (MAIT) cells are unconventional T cells with innate-like antimicrobial responsiveness. MAIT cells are known for MR1 (MH
Source: journals.aai.orgCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 2
While the coronavirus continues to infect people around the world, researchers at the University of Missouri have identified a specific protein inside the human body that plays a critical role in how the virus spreads from cell to cell after infection — a discovery that will help better understand the COVID-19 disease and could lead to the development of new antiviral drugs in the future. The…
Source: EurekAlert!Categories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 19
The multidisciplinary team of researchers found that BDGR-49 protects mice infected with deadly eastern equine encephalitis virus (EEEV) or Venezuelan equine encephalitis virus (VEEV).
Source: news.wisc.eduCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 0Counterintuitive effect of antiviral therapy on influenza A-SARS-CoV-2 coinfection due to viral interference - 1 year(s) ago
The resurgence of influenza and continued circulation of SARS-CoV-2 raise the question of how these viruses interact in a co-exposed host. Here we studied virus-virus and host-virus interactions during influenza A virus (IAV) -SARS-CoV-2 coinfection using differentiated cultures of the human airway epithelium. Coexposure to IAV enhanced the tissue antiviral response during SARS-CoV-2 infection…
Source: bioRxivCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Dual antiviral therapy for persistent COVID-19 and associated organizing pneumonia in an immunocompromised host - PubMed - 2 year(s) ago
The management of patients with prolonged viral shedding and COVID-19 symptoms remains unclear. Combining antivirals, as practiced in other infections, is theoretically advantageous. We present a case of persistent, symptomatic SARS-CoV2 infection and associated organizing pneumonia that was success …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Airway-delivered short-chain fatty acid acetate boosts antiviral immunity during rhinovirus infection - PubMed - 2 year(s) ago
SCFAs augments antiviral immunity and reduces virus load and pro-inflammatory responses during RV infection.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0Wyss researchers discover a new type of RNA that inhibits a broad range of viral infections - 2 year(s) ago
Novel immunostimulatory dsRNAs activate antiviral responses against multiple pandemic viruses in mouse and human organ chip models
Source: Wyss InstituteCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 2The association of antiviral drugs with COVID-19 morbidity: The retrospective analysis of a nationwide COVID-19 cohort - PubMed - 2 year(s) ago
Our findings demonstrated that antiviral drugs including lopinavir, ritonavir, and favipiravir were associated with negative clinical outcomes such as increased risks for lengthy hospital stay, ICU admission, and invasive mechanical ventilation requirement. Therefore, repurposing such agents without …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0
Do you have a plan for preventing flu complications in your patients? Join here for best practices on incorporating antiviral agents into patient care.
Source: MedscapeCategories: Latest Headlines, PediatricsTweet
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Mashup Score: 7
Researchers unravel the crystal structure of nsp14 — a key enzyme of SARS-CoV-2—paving the way for new antivirals.
Categories: Future of Medicine, Latest HeadlinesTweet
👓📖 Kick back and #review! Dr. Johan Sandberg (@SandbergLabKI) and colleagues at @CIM_Sweden @karolinskainst summarize recent progress and 💡 highlight outstanding questions regarding the emerging role of #MAIT cells in #antiviral immunity. @J_Immunol | https://t.co/Wvm39d7Vjn https://t.co/nRN2oM7LYw