• Mashup Score: 1
    Effects of aneuploidy on cell behaviour and function - Nature Reviews Molecular Cell Biology - 2 year(s) ago

    Aneuploidy affects organisms from early development through to aging and is a cause of pregnancy loss and cancer. Recent studies have increased our understanding of its mechanisms and how it can be both beneficial and detrimental to cells and organisms, depending on the karyotype and external cues. These insights shed light on its roles in human pathogenesis and on genome evolution.

    Source: Nature
    Categories: Allergy-Immunology, Latest Headlines
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      NatRevMCB

      Also in April issue #Review by Rong Li and Jin Zhu discussing how #aneuploidy affects cell function @RongLabOfficial @NUSingapore @JohnsHopkins #chromosomes #genomeinstability https://t.co/sZLRhL3BJ6 https://t.co/fPWWYELIjx

  • Mashup Score: 11
    Effects of aneuploidy on cell behaviour and function - Nature Reviews Molecular Cell Biology - 2 year(s) ago

    Aneuploidy affects organisms from early development through to aging and is a cause of pregnancy loss and cancer. Recent studies have increased our understanding of its mechanisms and how it can be both beneficial and detrimental to cells and organisms, depending on the karyotype and external cues. These insights shed light on its roles in human pathogenesis and on genome evolution.

    Source: Nature
    Categories: Allergy-Immunology, Latest Headlines
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      NatRevMCB

      New #Review by Rong Li and Jin Zhu discussing how #aneuploidy affects cell function @RongLabOfficial @NUSingapore @JohnsHopkins #chromosomes #genomeinstability https://t.co/sZLRhL3BJ6 https://t.co/nlDxMN6e2K

  • Mashup Score: 0
    Aneuploidy as a promoter and suppressor of malignant growth - 3 year(s) ago

    This Review discusses the diverse facets of cancer biology that are shaped by aneuploidy and highlights the distinct roles of aneuploidy as both a tumour promoter and an anticancer vulnerability.

    Source: Nature Reviews Cancer
    Categories: Hem/Onc News and Journals, Latest Headlines
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      NatureRevCancer

      NEW Review! A Vasudevan, J Sheltzer & co discuss the diverse facets of #cancerbiology that are shaped by #aneuploidy and highlight the distinct roles of aneuploidy as both a tumour promoter and an anticancer vulnerability. 🌟 https://t.co/bGZVW5nLrG @NatResCancer @JSheltzer

  • Mashup Score: 0
    Molecular signatures of aneuploidy-driven adaptive evolution - 4 year(s) ago

    Aneuploidy (abnormal chromosome number) can enable rapid adaptation to stress conditions, but it also entails fitness costs from gene imbalance. Here, the authors experimentally evolve yeast while forcing maintenance of aneuploidy to identify the mechanisms that promote tolerance of aneuploidy.

    Source: Nature Communications
    Categories: Healthcare Professionals
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      westr

      Molecular signatures of #aneuploidy-driven adaptive #evolution | Nature Communications ⁦@NatureComms⁩ #geneexpression https://t.co/mDQ0xxfENb