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Mashup Score: 0Patient-Reported Pulmonary Symptoms, Exacerbations, and Management in a Cohort of Patients With Alpha-1 Antitrypsin Deficiency - PubMed - 2 year(s) ago
Changes in usual pulmonary symptoms are not universally recognized as exacerbations. Patients’ perspectives in recognizing changes in pulmonary symptoms as exacerbation events are critical.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 2
The Delta (B.1.617.2) variant was the predominant UK circulating SARS-CoV-2 strain between May and December 2021. How Delta infection compares with previous variants is unknown. This prospective observational cohort study assessed symptomatic adults participating in the app-based COVID Symptom Study …
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 0
Background The evolution of SARS-CoV-2 has led to the emergence of several new variants, and few data are available on the impact of vaccination on SARS-CoV-2 variants. We aimed to assess the association between natural (previous infection) and induced (partial or complete vaccination) exposure to SARS-CoV-2 and the onset of new infection supported by the delta variant, and of comparing it with…
Source: BioMed CentralCategories: General Medicine Journals and Societies, Latest HeadlinesTweet
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Mashup Score: 49
Emerging SARS-CoV-2 variants of concern/interest (VOC/VOI) raise questions about effectiveness of neutralizing antibodies derived from infection or vaccination. As the population immunity to SARS-CoV-2 has become more complex due to prior infection and/or vaccination, understanding the antigenic relationship between variants is needed. Here, we have assessed in total 104 blood specimens from…
Source: medRxivCategories: Infectious Disease, Latest HeadlinesTweet-
This is also what we have seen in our study: No matter if your prior infection was #SARSCoV2 in 2020, #Alpha, #Beta, #Gamma or #Delta, protection against #Omicron is poor. Omicron is most likely a new serotype that escapes immunity to earlier infection. https://t.co/C8Wl65mcqc https://t.co/ERIE27qiHE
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Mashup Score: 1Alpha-gal sensitization among young adults is associated with male sex and polysensitization - 2 year(s) ago
Galactose-α-1,3-galactose (α-Gal) syndrome (AGS) is characterized by delayed severe allergic reactions after consumption of mammalian meat or mammalian-derived products and is caused by immunoglobulin E (IgE) antibodies against the carbohydrate α-Gal.1,2 AGS is most common at middle age, and the route of sensitization appears to be through tick bites.2,3 The prevalence of IgE reactivity to α-Gal…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 3Alpha-1 Antitrypsin MZ Heterozygosity is an Endotype of Chronic Obstructive Pulmonary Disease - PubMed - 2 year(s) ago
Carriers of the alpha-1 antitrypsin Z allele (MZ heterozygotes) with COPD had lower lung function and more emphysema compared to MM subjects with COPD. Taken with the subtle differences in gene expression between the two groups, our findings suggest that MZ subjects represent an endotype of COPD.
Source: PubMedCategories: Latest Headlines, PulmonologyTweet
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Mashup Score: 33
Background Twenty-one months into the pandemic, the extent to which young children get infected and transmit SARS-CoV-2 in school settings remains controversial, in particular with variants of concern. We report a prospective epidemiological, virological and serological investigation of a SARS-CoV-2 outbreak in a primary school in Geneva, Switzerland, in April-May 2021. Methods This outbreak…
Source: medRxivCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 0ALPHA-GAL SENSITIZATION AMONG YOUNG ADULTS IS ASSOCIATED WITH MALE SEX AND POLYSENSITIZATION - 2 year(s) ago
Article InfoPublication HistoryAccepted: October 5, 2021Received in revised form: October 4, 2021Received: April 29, 2021Publication stageIn Press Journal Pre-ProofFootnotesSources of funding:The study was conducted with support from by grants from Region Stockholm (ALF project, research positions and for cohort and database…
Categories: Allergy-Immunology, Latest HeadlinesTweet
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Mashup Score: 0Delta Variant Doubles Hospitalizations Compared to Alpha - 3 year(s) ago
A study from the United Kingdom shows the newer variant led to an increase in severe infections in a mostly unvaccinated population.
Source: Contagion LiveCategories: Infectious Disease, Latest HeadlinesTweet
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Mashup Score: 56
Original Article from The New England Journal of Medicine — Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant
Source: New England Journal of MedicineCategories: Critical Care, Latest HeadlinesTweet
#Patient- #Reported #Pulmonary #Symptoms, #Exacerbations, and #Management in a #Cohort of Patients With #Alpha-1 #Antitrypsin #Deficiency https://t.co/HHKV6UXoln https://t.co/2JdFjNVHED