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Mashup Score: 5Allogeneic Hematopoietic Cell Transplantation for Blastic Plasmacytoid Dendritic Cell Neoplasm: a CIBMTR analysis - 6 month(s) ago
Key Points. Age 60 or older and remission status at time of allo-HCT (CR2/PIF/Relapse vs CR1) was predictive of inferior overall survival.Use of myeloablative c
Source: ashpublications.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 4Post-Transplant Cyclophosphamide-Based GVHD Prophylaxis Bests Standard Regimen in Phase III Study | ASH Clinical News | American Society of Hematology - 6 month(s) ago
Katie Robinson is a medical writer based in New York. Patients undergoing a human leukocyte antigen (HLA)-matched allogeneic hematopoietic cell transplantation (alloHCT) with reduced-intensity conditioning who received a prophylaxis regimen of cyclophosphamide, tacrolimus, and mycophenolate mofetil had longer graft-versus-host disease (GVHD)-free, relapse-free survival than those who received standard prophylaxis of tacrolimus and methotrexate. These findings from a phase III study were published in the
Source: ashpublications.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Cyclosporine impact on tolerance induction after allo-HCT - 7 month(s) ago
Senjo H, Harada S, Kubota SI, et al. Calcineurin Inhibitor Inhibits Tolerance Induction by Suppressing Terminal Exhaustion of Donor T Cells After Allo-HCT. Blood. 2023; (doi:…
Source: nucleus.astct.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Researchers may have uncovered why, despite routine prophylaxis, many #alloHCT recipients fail to attain long-term tolerance w/o development of chronic #GVHD, and it has to do with transitory-tex and terminally-tex T cells. Read more on Nucleus: https://t.co/fN4HklI9Je #CARTcells https://t.co/RMEhTBKflg
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Mashup Score: 0
Findings from a phase 3 trial published in JAMA Oncology suggest allo-HCT may not provide an OS benefit for patients with intermediate-risk acute myeloid leukemia during first complete remission.
Source: www.targetedonc.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
A cohort study identified an association between exposure to several commonly used antibiotics and acute GVHD in patients who underwent allogeneic hematopoietic cell transplantation.
Source: Oncology Nurse AdvisorCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Maintenance with ivosidenib post-HCT in IDH1-mutated AML - 10 month(s) ago
Fathi AT, Kim HT, Soiffer RJ, et al. Multi-Center Phase I Trial of Ivosidenib as Maintenance Treatment Following Allogeneic Hematopoietic Cell Transplantation for IDH1-Mutated Acute Myeloid Leukemia. Clinical Cancer Research. 2023; (doi: 10.1158/1078-0432.CCR-23-0182). A Phase I trial testing the isocitrate dehydrogenase 1 (IDH1) inhibitor ivosidenib as maintenance therapy in patients with…
Source: ASTCT NucleusCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2Value of DNA sequencing pre-HCT for AML patients - 10 month(s) ago
Dillon LW, Gui G, Page KM, et al. DNA Sequencing to Detect Residual Disease in Adults with Acute Myeloid Leukemia Prior to Hematopoietic Cell Transplant. JAMA. 2023; 329 (9): 745 (doi: 10.1001/jama.2023.1363). In patients with acute myeloid leukemia (AML) in first remission before undergoing allogeneic hematopoietic cell transplant, new research shows poorer outcomes for individuals with…
Source: ASTCT NucleusCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 3
Background: Allogeneic haematopoietic cell transplantation (alloHCT) is a life-saving procedure for many patients with haematological disease. However, its toxi
Source: papers.ssrn.comCategories: Hematologists1, Latest HeadlinesTweet
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Mashup Score: 1Primary AlloHCT During First Complete Remission and Overall Survival Rates Among Patients With AML - 11 month(s) ago
According to the results of a phase 3 trial, primary allogeneic hematopoietic cell transplant was not correlated with superior overall survival rates among patients with AML, compared with consolidation therapy.
Source: HMP Global Learning NetworkCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Wolters Kluwer Health - 11 month(s) ago
JavaScript Error JavaScript has been disabled on your browser. You must enable it to continue. Here’s how to enable JavaScript in the following browsers: Internet Explorer From the Tools menu, select Options Click the Content tab Select Enable JavaScript Firefox From the Tools…
Source: lww.comCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
How well does Allogeneic Hematopoietic Cell Transplantation #AlloHCT work for Blastic Plasmacytoid Dendritic Cell Neoplasm #BPDCNsm ? Our new @CIBMTR analysis with many outstanding investigators @BloodAdvances @YaleCancer https://t.co/juMTRHAKcW