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Mashup Score: 8Nutrient regulation of bone marrow adipose tissue: skeletal implications of weight loss - 7 month(s) ago
Nature Reviews Endocrinology – This Review examines the origins of marrow adipocytes and their function under normal or pathological conditions. Regulation of bone marrow adipose tissue by nutrient…
Source: www.nature.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0Do adipocytes serve as a reservoir for severe acute respiratory syndrome coronavirus-2? - 8 month(s) ago
Obesity is associated with a higher risk of severe coronavirus disease 2019 (COVID-19) and increased mortality. In the current study, we have investigated the expression of ACE2, NRP1, and HMGB1, known to facilitate severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cell entry, in adipose tissue from non-COVID-19 control patients with normal weight, overweight, and obesity. All factors…
Source: joeCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0The evolving view of thermogenic adipocytes — ontogeny, niche and function - Nature Reviews Endocrinology - 1 year(s) ago
This Review highlights the ontogeny of thermogenic adipocytes, regulation of the adipose tissue microenvironment and inter-organ communication between adipose and other tissues. In addition, activation of thermogenic adipose tissue in humans and animal models is discussed, as well as the therapeutic potential of thermogenic adipose tissue.
Source: NatureCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1The evolving view of thermogenic adipocytes — ontogeny, niche and function - Nature Reviews Endocrinology - 1 year(s) ago
This Review highlights the ontogeny of thermogenic adipocytes, regulation of the adipose tissue microenvironment and inter-organ communication between adipose and other tissues. In addition, activation of thermogenic adipose tissue in humans and animal models is discussed, as well as the therapeutic potential of thermogenic adipose tissue.
Source: NatureCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0AcroBATics: how dying brown adipocytes trigger browning - Nature Reviews Endocrinology - 1 year(s) ago
Thermogenic brown and beige adipocytes have gained much attention as potential therapeutic targets in obesity and related cardiometabolic disease. A recent paper in Nature identifies inosine, released from apoptotic brown adipocytes, as an inducer of thermogenic adipose tissue, thereby uncovering an unexpected and novel mechanism of adipose tissue plasticity.
Source: NatureCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 5Thematic Issue: Lipids and Adipocytes 2022 - 1 year(s) ago
September 2022
Source: Oxford AcademicCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 0Insulin sensitive human adipocytes for in vitro studies - 2 year(s) ago
Adipocyte insulin resistance is a driving force for systemic insulin resistance. Advances in human stem cell culture have established conditions for human adipocytes that give rise to a reproducible population of adipocytes that retain a high level of insulin sensitivity, paving the way for high throughput screening approaches.
Source: www.nature.comCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1
Background: The ADRB3 (β3-adrenergic receptors), which is predominantly expressed in brown adipose tissue (BAT), can activate BAT and improve metabolic health. Previous studies indicate that the endo
Source: Circulation ResearchCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 4Adipose tissue lipolysis controlled by endothelial cells - Nature Reviews Endocrinology - 2 year(s) ago
By identifying a new means of communication between endothelial cells and adipocytes, researchers provide evidence that the endothelial cells actively provoke lipid release from adipocytes to support capillary growth. This crosstalk ultimately helps to maintain metabolic health in obesity.
Source: NatureCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 3Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics - Nature Reviews Endocrinology - 2 year(s) ago
White adipocyte metabolism is important for the regulation of systemic metabolism and is often dysregulated in various conditions, such as cancer and type 2 diabetes mellitus. In this Review, Langin and colleagues provide an overview of lipid metabolism in white adipocytes and the related metabolism of glucose and discuss how these pathways provide therapeutic targets in metabolic disorders.
Source: NatureCategories: Endocrinology, Latest HeadlinesTweet
Out now - Clifford J. Rosen & Mark C. Horowitz examine the origins of #bone marrow #adipocytes and their function under normal and pathological conditions (£) https://t.co/KjddnB0P1D https://t.co/AgOwZRr4KX