• Mashup Score: 0

    Obesity is associated with a higher risk of severe coronavirus disease 2019 (COVID-19) and increased mortality. In the current study, we have investigated the expression of ACE2, NRP1, and HMGB1, known to facilitate severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) cell entry, in adipose tissue from non-COVID-19 control patients with normal weight, overweight, and obesity. All factors…

    Tweet Tweets with this article
    • Do #adipocytes serve as a reservoir for severe acute respiratory symptom #coronavirus-2? By Charlotte Steenblock et al. (@tudresden_de @Unispital_USZ) the latest article from our Insulin Resistance and Type 2 Diabetes Mellitus themed collection. ➡️ https://t.co/n09p2pBYhS https://t.co/VhtlOfepJu

  • Mashup Score: 0

    Thermogenic brown and beige adipocytes have gained much attention as potential therapeutic targets in obesity and related cardiometabolic disease. A recent paper in Nature identifies inosine, released from apoptotic brown adipocytes, as an inducer of thermogenic adipose tissue, thereby uncovering an unexpected and novel mechanism of adipose tissue plasticity.

    Tweet Tweets with this article
    • In the November issue: Julia Zinngrebe & Pamela Fischer-Posovszky discuss a paper on how dying brown #adipocytes trigger browning (£) https://t.co/vjhJMHoBcY https://t.co/qDDg1b7AaD

  • Mashup Score: 0

    Adipocyte insulin resistance is a driving force for systemic insulin resistance. Advances in human stem cell culture have established conditions for human adipocytes that give rise to a reproducible population of adipocytes that retain a high level of insulin sensitivity, paving the way for high throughput screening approaches.

    Tweet Tweets with this article
    • In the October issue, Leon G. Straub & Philipp E. Scherer discuss a paper on the development of an #insulin resistance model in human stem cell–derived #adipocytes https://t.co/2B1rL58TOO https://t.co/Z2L1ogIcPg

  • Mashup Score: 4

    By identifying a new means of communication between endothelial cells and adipocytes, researchers provide evidence that the endothelial cells actively provoke lipid release from adipocytes to support capillary growth. This crosstalk ultimately helps to maintain metabolic health in obesity.

    Tweet Tweets with this article
    • Online now! A News & Views by Martina Rudnicki & Tara L. Haas that discusses crosstalk between #adipocytes and endothelial cells (£) https://t.co/9lu1jNgHUj https://t.co/SsAG1DGyZc

  • Mashup Score: 3

    White adipocyte metabolism is important for the regulation of systemic metabolism and is often dysregulated in various conditions, such as cancer and type 2 diabetes mellitus. In this Review, Langin and colleagues provide an overview of lipid metabolism in white adipocytes and the related metabolism of glucose and discuss how these pathways provide therapeutic targets in metabolic disorders.

    Tweet Tweets with this article
    • Pauline Morigny, Jeremie Boucher, Peter Arner & Dominique Langin review current understanding of glucose and lipid #metabolic pathways in white #adipocytes (£) https://t.co/us51tjMBLq https://t.co/G0fFcjjdgE