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    Acinetobacterstrains have become a cause for concern — particularly among critically ill, hospitalized patients — owing to the spread of multidrug resistance and risk of epidemics. Here, the authors discuss the current knowledge of the genusAcinetobacter, with the emphasis on the clinically most important species, Acinetobacter baumannii.

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    • 7/ #Acinetobacter has high frequency of an extreme drug resistance (XDR) phenotype The resistance is mediated by all of the major resistance mechanisms: modification of target sites, enzymatic inactivation, active efflux and decreased influx of drugs https://t.co/mXXW72ibAt

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    Acinetobacter species are considered dreadful pathogens for patients in the intensive care unit as they are often multidrug resistant (MDR), leading to difficult-to-treat infections and, occasionally, therapeutic dead ends. Carbapenem-resistant Acinetobacter are in the top position of “the WHO priority pathogens”, for which novel antibiotics are desperately needed. The carbapenem-resistance is…

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    • RT @LancetMicrobe: New correspondence> Acquired carbapenemase in #Acinetobacter during the pre-antibiotic era https://t.co/fdGlOXOZwP #AMR

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    Conceptually, the “control of gut overgrowth” (COGO) is key in mediating prevention against infection with Gram-negative bacilli by topical antibiotic prophylaxis, a common constituent of selective digestive decontamination (SDD) regimens. However, the relative importance of the other SDD components, enteral and protocolized parenteral antibiotic prophylaxis, versus other methods of infection…

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    • #CritCare #OpenAccess https://t.co/lChiadHmXd Control of #gut overgrowth concept (#COGO) by a structural #equation #modeling: #Pseudomonas & #Acinetobacter #infection incidence in #ICUs #FOAMed #FOAMcc #antibiotic #prophylaxis #bacteremia #decontamination @ISICEM @jlvincen https://t.co/zu4fGM5urF