• Mashup Score: 40

    Summary:. The current approaches for cancer drug development lag behind an accelerated need in the field for a fast and efficient method for evaluating drugs in the personalized medicine era. In that regard, N-of-1 studies emerge as a potential addition to the drug development arsenal, although there are several considerations before its broad application becomes feasible. In essence, N-of-1…

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    • N-of-1 Trials in Cancer Drug Development | Cancer Discovery | American Association for Cancer Research https://t.co/AG8gCOKZ6s

  • Mashup Score: 2

    The addition of pembrolizumab to gemcitabine and cisplatin conferred a statistically significant and clinically meaningful survival benefit for patients with advanced biliary tract cancer, according to results of the KEYNOTE-966 study. “We were encouraged to see the consistency of benefit across geographic regions, including non-Asian regions, and across PD-L1 expression

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    • Pembrolizumab plus chemotherapy prolongs survival in advanced biliary tract cancer. https://t.co/n0vvFpvIgc #AACR2023 #AACR23 @AACR #HemOnc #OncAlert #MedEd #tractcancer

  • Mashup Score: 2

    Patients with resectable non-small cell lung cancer who received perioperative durvalumab with neoadjuvant chemotherapy had significantly longer EFS and higher pathologic complete response rates than those who received chemotherapy alone.The combination also had a manageable safety profile consistent with previous studies, according to results of the randomized, double-blind phase 3 AEGEAN trial,

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    • Perioperative durvalumab-based therapy reduces risk for adverse lung cancer outcomes. https://t.co/RBCWFwBRmR #AACR2023 #AACR23 @AACR #HemOnc #OncAlert #MedEd