Abstract. T cell activation is an essential step in chimeric Ag receptor (CAR) T (CAR T) cell manufacturing and is accomplished by the addition of activato
The axe, which Ben found on Shoreham Beach when he was six, could be up to 60,000 years old.
CD4+ T helper (Th) cell differentiation depends on regulatory networks that enforce lineage commitment while suppressing alternative fates. In a recent issue of Nature, Hou…
Nature Reviews Immunology – A preprint by Chung et al. presents a framework for the use of transcriptomic and epigenomic data to identify novel transcription…
Two couples in California discovered they were raising each other’s genetic children. Should they switch their girls?
“A blog about allergy, asthma & immunology”
Central tolerance restricts T cells that target self-antigens. In this issue of Immunity, Abdelfattah et al. describe a method to generate self-reactive T cell receptors (TCRs) by directed…
“A blog about allergy, asthma & immunology”
The FDA has cleared the investigational new drug application for STAR-0310 as a potential treatment for atopic dermatitis and other diseases, Astria Therapeutics announced in…
Gopee and colleagues’ recent analyses of diverse high-dimensional datasets of prenatal and adult skin, together with data from complex skin organoids, uncover the important contributions…
Rheumatoid arthritis (RA) is driven by antigen-specific T cell responses targeting the joints. MacDonald et al. define the range of dendritic cell (DC) populations within joints of…
