Science
What does being a scientist mean to you? Does it involve field-work sifting through the jungle? Or spending time peering at a tiny organism through a microscope? While these types of tasks come to…
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An Alzheimer’s disease–associated mutation in the kinase PKCη concentrates its activity at the Golgi.
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A new class of editor has improved delivery, durability, tunability, and safety
Elephants gesture to signal what they want—just like us
New experiments show elephants use a wide range of movements to express their desires
Modern Healthcare
Children’s hospitals say the trickle-down effects of reduced Medicaid funding will hurt the very patient populations the program was built to protect.
Glymphatic dysfunction in Alzheimer’s disease: A critical appraisal
Thirteen years after the initial publication defining the glymphatic system, we critically reappraise the role of its dysfunction in Alzheimer’s disease (AD). Our understanding of…
Biorhythms derived from consumer wearables predict postoperative complications in children
Biorhythms (activity and heart rate patterns) from consumer wearables can predict complications in children after appendectomy.
Pterosaur died with belly full of plants—a fossil first
New discovery confirms the long-debated hypothesis that the ancient winged reptiles ate plants
Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s disease–linked LRRK2-mutant mice
LRRK2 inhibition restores a cilia-dependent, neuroprotective signaling circuit in Parkinsonian mice.
The U.S. reneged on aid commitments. Nepal’s malnourished children are paying the price
Hard-won progress in improving child and maternal nutrition hangs in the balance
Expanding the reach of molecular glue degraders
An epitope-centric screening approach widens the neosubstrate landscape for targeted protein degradation