Headlines Covid-19 Specialties Trending Feeds Videos

The authors report on prospective exploratory analyses of circulating tumour DNA in an urothelial carcinoma immunotherapy clinical...

The Moderna (mRNA-1273) and Pfizer–BioNTech (BNT162b2) vaccines elicit anti-RBD antibodies similar to those elicited through natural infection with SARS-CoV-2, but their potent neutralizing activity...

Though SARS-CoV-2 primarily targets the respiratory system, patients and survivors can suffer neurological symptoms1–3. Yet, an unbiased understanding of the cellular and molecular processes...

Rapidly-emerging variants jeopardize antibody-based countermeasures against SARS-CoV-2. While cell culture experiments have demonstrated loss of potency of several anti-spike neutralizing antibodies against SARS-CoV-2 variant...

Though SARS-CoV-2 primarily targets the respiratory system, patients and survivors can suffer neurological symptoms1–3. Yet, an unbiased understanding of the cellular and molecular processes...

Single-cell RNA sequencing and imaging of macrophages in human non-small cell lung cancer and in a mouse model of lung adenocarcinoma show that tissue-resident...

  • ScRNA-seq of tumour-associated leukocytes reveal distinct populations of macrophages enriched in human and mouse lung tumours, with tissue-resident macrophages found to promoting EMT, invasiveness & evasion of adaptive immunity during tumour formation: https://t.co/t6eJiIYNjA - view on twitter

Results of an exploratory interim analysis from a phase I trial show that an RNA vaccine targeted towards four melanoma-associated antigens produces durable objective...

SARS-CoV-2 infection induces long-lived bone marrow plasma cells that correlate with anti-SARS-CoV-2 spike protein antibody titres in individuals who have recovered from...

  • 1more paper from today from same group but this time in naturally infected patients. Took 77 participants with mild infection; antibodies may wane over time (4-11 months) but did bone marrow biopsies in 18 & saw development of long-lived B memory cells https://t.co/1GK3FEnLyV - view on twitter

  • Must add here that memory B cells also seen in the germinal centers (stored in places like lymph nodes, bone marrow) from those who have had natural infection. This study examines those with even mild infection, did bone marrow biopsies, found memory B https://t.co/1GK3FEnLyV - view on twitter

The hippocampus geometrically represents both physical location and abstract variables on a neural manifold in mice performing a decision-making task in virtual...

Following its emergence in late 2019, the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)1,2 has been tracked via phylogenetic analysis of viral...