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Here, the authors present two well preserved fossil lizard skulls from the Late Jurassic of North America. These fossils, placed at the base of...

Singh and colleagues show that PDAC phenotypic plasticity is regulated via AP1 enhancer remodeling and modulated by TNF-α+ macrophages and pharmacological inhibition of the...

Here, the authors present two well preserved fossil lizard skulls from the Late Jurassic of North America. These fossils, placed at the base of...

Zhu et al. develop a deep learning method to precisely infer single-trial neural dynamics from calcium imaging with subframe temporal resolution, which shows improvement...

Glycosylation is a common modification that can affect protein stability and interactions. In this Review, the authors discuss the role of glycosylation in rheumatic...

Evolution of the SARS-CoV-2 spike protein is likely driven by many factors, including immune escape and receptor binding. Here, by measuring the binding affinity...

Nature Reviews Endocrinology – Tirzepatide highly effective for weight...

Halbrook et al. report two metabolic subgroups of pancreatic ductal adenocarcinoma cells defined by differential integrated stress response and asparagine production that permit symbiosis...

Smoldering multiple myeloma (SMM) is an asymptomatic precursor state of multiple myeloma (MM). Recently, MM was redefined to include biomarkers predicting a high risk...

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    No biomarker in medicine is perfect. Numerous investigators are working on improving the predictive ability of biomarkers in smoldering myeloma. While we try to add more genomic variables, here is a scoring system that works well which I use. @mvmateos https://t.co/fLCqtrvLSN - view on twitter

Smoldering multiple myeloma (SMM) is an asymptomatic condition that occupies a space between monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) along...