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Effect of Telephone Calls on Depression and Anxiety Among Adults During the Coronavirus Disease 2019 Pandemic

posted 20 hours


Mashup Score: 81

JAMA Network - This randomized clinical trial examines whether a layperson-delivered, empathy-focused program of telephone calls could rapidly improve loneliness, depression, and anxiety in at-risk...

  • Fabulous trial reduced loneliness, depression, and anxiety in Meals on Wheels participants who live alone over four weeks. How? College volunteers w 2 hrs training simply called a roster of 6-9 folks 2-5X/week (elders' choice) to ask how they are. https://t.co/XjzamfhCkJ

Identifying COVID-19 Risk Through Observational Studies to Inform Control Measures

posted 2 days


Mashup Score: 23

JAMA Network - This JAMA Insights Clinical Update from the CDC’s COVID-19 Response Team discusses the importance of observational data for identifying behaviors associated with SARS-CoV-2 transmission,...

  • Dining in restaurants associated with more than double the risk of #COVID19, presumably due to inability to #WearAMask while eating. Get takeout or delivery. Tip as generously as you can. https://t.co/wsxiQco7hr

Anaphylaxis After First Dose of the Pfizer-BioNTech COVID-19 Vaccination

posted 2 days


Mashup Score: 18

JAMA Network - This JAMA Insights review provides clinical details of anaphylactic reactions reported to and verified by the CDC in the first week of use of...

  • Per @CDCgov, 21 anaphylaxis cases occurred in the 1st week of @pfizer-BioNTech #COVID19 vaccine administration (11.1 per 1M doses): 4 patients (19%) hospitalized (3 in ICU), 17 (81%) managed in ED, 20 discharged; no known deaths https://t.co/sL55qhZWo2

Risk of Progression to Diabetes Among Older Adults With Prediabetes

posted 15 hours


Mashup Score: 12

JAMA Network - This cohort study of older adults without diabetes compares different prediabetes definitions and characterizes the risks of prediabetes and diabetes in this...

Patient Information: Treatment of Alcohol Use Disorder

posted 2 days


Mashup Score: 11

JAMA Network - This JAMA Patient Page explains the medications (naltrexone, acamprosate, disulfiram) and behavioral treatments (cognitive behavior therapy [CBT]) used to manage alcohol use...

AEQUANIMITAS

posted 2 days


Mashup Score: 9

JAMA Network - IF SIR WILLIAM OSLER were to have summed up the philosophy of his life in a single word, it might well have been aequanimitas....

Pregnant People Getting Mixed Messages About COVID-19 Vaccines

posted 15 hours


Mashup Score: 9

JAMA Network - This Medical News Quick Uptake discusses the evidence in favor of administering COVID-19 vaccines to pregnant...

Hydrocortisone, Vitamin C, and Thiamine for Treatment of Sepsis—Making Evidence Matter

posted 13 hours


Mashup Score: 9

JAMA Network - The randomized trial, alone or as part of a meta-analysis, is the pinnacle of the evidence pyramid.1 Rigorously performed randomized trials offer key insights...

  • Enthusiasm for HC-vitaminC-thiamine (HAT) as a treatment for #sepsis arose from an obs study that reported mortality reduction in 47 patients vs historical controls. 6 RCTs since have been unable to confirm the effect https://t.co/SpG8JkV408 @seymoc @PittCCM

Effect of Subcutaneous Semaglutide on Body Weight in Adults With Obesity

posted 12 hours


Mashup Score: 7

JAMA Network - This randomized clinical trial compares the effects of once-weekly subcutaneous semaglutide vs placebo for weight management as an adjunct to intensive behavioral therapy with...

  • In this RCT, once-weekly subcutaneous semaglutide used as an adjunct to intensive behavioral therapy & low-calorie diet led significantly greater weight loss vs placebo over 68 weeks among adults w #overweight or #obesity w/o #diabetes https://t.co/xFedvckUUj @PennMedicine #STEP3

Laparoscopic Sigmoid Resection vs Conservative Treatment in Improving Quality of Life in Diverticulitis

posted 2 days


Mashup Score: 6

JAMA Network - This randomized clinical trial assesses whether sigmoid resection is superior to conservative treatment in improving quality of life of patients with recurrent, complicated, or...