EClinicalMedicine
EClinicalMedicine is a new open access clinical journal, published by The Lancet, helping frontline health practitioners solve the challenges of health care.
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Endocrine health in survivors of adult-onset cancer
Long-term survivors of cancer (ie, the patient who is considered cured or for whom the disease is under long-term control and unlikely to recur) are…
Disparities in fragility fracture and osteoporosis care in Africa
Over the coming decades, Africa is predicted to have the greatest increase in the number of older people worldwide. Older people in this region spend…
Improving epilepsy diagnosis across the lifespan: approaches and innovations
Epilepsy diagnosis is often delayed or inaccurate, exposing people to ongoing seizures and their substantial consequences until effective treatment is initiated. Important factors contributing to…
Denosumab in the treatment of osteoporosis associated with chronic kidney disease
Osteoporosis is a substantial health concern worldwide, particularly among individuals with advanced chronic kidney disease (CKD). In this population, bone fragility is a prevalent complication…
Optimising zoledronate treatment holiday duration without loss of fracture prevention
Osteoporosis is characterised by reduced bone mass and disordered bone microstructure, which collectively result in increased fracture risk. Data from the National Health and Nutrition…
Duration of fracture prevention after zoledronate treatment in women with osteopenia: observational follow-up of a 6-year randomised controlled trial to 10 years
The reduced fracture rates following zoledronate in the core trial were substantially maintained for 1·5–3·5 years after the last zoledronate infusion, but not thereafter.
Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicentre, open-label, randomised controlled trial
In patients with non-flow-limiting vulnerable coronary plaques, preventive percutaneous coronary intervention reduced major adverse cardiac events arising from high-risk vulnerable plaques, compared with optimal medical…
Frailty assessment in the care of older people with haematological malignancies
Frailty, defined as an age-related state of increased vulnerability to acute stressors, is a major challenge in the care of older people with haematological malignancies.…
Air pollution exposure and cardiometabolic risk
The Global Burden of Disease assessment estimates that 20% of global type 2 diabetes cases are related to chronic exposure to particulate matter (PM) with…
Glycaemic index as part of the diabetes prevention strategy
The study by Victoria Miller and colleagues1 in The Lancet Diabetes & Endocrinology adds to and extends the growing body of evidence of the importance…