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A clinical stage multivalent SARS-CoV-2 spike receptor-binding domain nanoparticle (RBD-NP) vaccine is protective in mice after a single immunization and elicits strong antibody responses...

PE4 and PE5 are efficient and precise prime editing systems developed by leveraging insights into the way DNA repair pathways impact genome editing...

PE4 and PE5 are efficient and precise prime editing systems developed by leveraging insights into the way DNA repair pathways impact genome editing...

PE4 and PE5 are efficient and precise prime editing systems developed by leveraging insights into the way DNA repair pathways impact genome editing...

An interconnected network of 266 transcription factors and promoters of 47 mycorrhiza-related genes highlights a PHR-centered arbuscular mycorrhizal symbiosis transcriptional regulatory network in rice,...

Intratumoral heterogeneity in the human pancreatic tumor microenvironment is not random but originates in well-definable regional tissue states. The underlying sub-tumor microenvironments shape regional...

Intratumoral heterogeneity in the human pancreatic tumor microenvironment is not random but originates in well-definable regional tissue states. The underlying sub-tumor microenvironments shape regional...

A transient retrotransposon induction in mammalian preimplantation embryos yields numerous gene regulatory events. Deletion of an MT2B2 retrotransposon promoter abolishes a Cdk2ap1 isoform (Cdk2ap1ΔN),...

Biosensors responding to protein conformation enable single molecule detection of active proteins in live cells, affording insights into both cellular function and...