Mashup Score:5
Cell Host & MicrobeArticles from: Cell Host & Microbe
Mashup Score:140
Cell Host & MicrobeAntibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein - 2 weeks
Mashup Score:140
The Omicron BA.1 and BA.2 variants have unprecedented numbers of nonsynonymous and indel spike protein mutations. Javanmardi et al. report the antigenicity, expression, and...
-
BA.1 vs BA.2 "We conclude that the continuing accumulation of NTD mutations will further alter the conformational equilibrium and stability of the spike protein to allow for the accumulation of new, more virulent mutations in the RBD" https://t.co/QDXLuJS7Rp @cellhostmicrobe https://t.co/QDXLuJS7Rp - view on twitter
Mashup Score:92
Cell Host & MicrobeYu et al. conducted a longitudinal study on pre-COVID pandemic samples, and found that common cold coronaviruses (CCC) responses are sustained and relatively constant...
-
Another reason for protection in some people pre-Covid High common cold coronavirus-specific CD4+ T cell reactivity is associated with pre-existing SARS-CoV-2 immunity https://t.co/ggtVfrK7Wi @cellhostmicrobe @SetteLab https://t.co/ggtVfrK7Wi - view on twitter
Mashup Score:290
Cell Host & MicrobeThe Omicron Spike protein contains numerous mutations thought to play key roles in efficient spread and immune evasion of this currently dominating SARS-CoV-2 variant....
-
How did the 57 spike mutations in BA.1 and then BA.2 (from Wuhan Hu-1, ancestral) lead to immune escape and resistance to many monoclonal antibodies? https://t.co/pcsisNgoeD @cellhostmicrobe Need that functional mutation analysis updated for BA.5 https://t.co/pcsisNgoeD - view on twitter
Mashup Score:173
Cell Host & MicrobeCan maternal-child microbial seeding interventions improve the health of infants delivered by Cesarean section? - 3 months
Mashup Score:173
Maternal-child microbial seeding interventions expose Cesarean-section (C-section)-delivered infants to the maternal microbiome they bypass during Cesarean delivery. It is theorized such interventions restore the...
-
"Can maternal-child microbial seeding interventions improve the health of infants delivered by cesarean section?" Read more in @cellhostmicrobe: https://t.co/ktSJt7yT8v Suchitra K. Hourigan, Maria Gloria Dominguez-Bello, & @noeltmueller @NIAIDNews https://t.co/ktSJt7yT8v - view on twitter
Mashup Score:5
Cell Host & MicrobeRichardson et al. show that SARS-CoV-2 Omicron infection in unvaccinated individuals triggers potent antibody responses; however, cross-reactivity against variants of concern is poor. In contrast,...
-
SARS-CoV-2 Omicron triggers cross-reactive neutralization and Fc effector functions in previously vaccinated, but not unvaccinated, individuals - full article by Penny L. Moore @nicd_sa in @cellhostmicrobe #AAI2022 https://t.co/lhWYT7fATB - view on twitter
More coverage:
#aai2022
Mashup Score:14
Cell Host & MicrobeCommensal segmented filamentous bacteria-derived retinoic acid primes host defense to intestinal infection - 3 months
Mashup Score:14
Interactions with the microbiota alter host defense against pathogens. Woo et al. report that commensal bacteria, including segmented filamentous bacteria, can express aldehyde dehydrogenase (aldh)...
-
Commensal segmented filamentous bacteria-derived retinoic acid primes host defense to intestinal infection Theresa Alenghat @AlenghatLab et al. @cellhostmicrobe #AAI2022 https://t.co/hmnIkDfIFk - view on twitter
More coverage:
#aai2022
Mashup Score:122
Cell Host & MicrobeAntibody Evasion of SARS-CoV-2 Omicron BA.1, BA.1.1, BA.2 and BA.3 Sub-lineages - 3 months
Mashup Score:122
Ai et al. report side-by-side susceptibility profiles of Omicron BA.1, BA.1.1, BA.2 and BA.3 sub-lineages to BBIBP-CorV vaccine-elicited neutralization, finding substantial evasion against two-dose,...
Mashup Score:8
Cell Host & MicrobeAberrant gut-microbiota-immune-brain axis development in premature neonates with brain damage - 3 months
Mashup Score:8
Seki et al. performed a comprehensive, time-resolved analysis of the gut microbiota-immune-brain axis in extremely premature infants. This analysis links early-life microbiome establishment to immunological...
-
Lukas Wisgrill @WisgrillL et al. explore "Aberrant gut-microbiota-immune-brain axis development in premature neonates with brain damage" @cellhostmicrobe #AAI2022 https://t.co/2ASyJKAZNo - view on twitter
More coverage:
#aai2022
Mashup Score:269
Cell Host & MicrobeThe SARS-CoV-2 Omicron variant contains at least three main sublineages that harbor shared and unique spike protein mutations. Arora et al. show that sublineages...
-
Reflecting the immune escape features of Omicron and its subvariants, relative lack of sensitivity to monoclonal antibody therapy neutralization. BA.2.12.1 (soon to be US dominant) is more resistant than BA.2, especially to Cilgavimab https://t.co/473mHTl54J @cellhostmicrobe https://t.co/473mHTl54J - view on twitter
Using a triple-blind randomized clinical trial, Asbury et al. demonstrate that human milk enriched with human- versus bovine-milk-based fortifiers alters the gastrointestinal microbiota of infants...
"Human Milk Nutrient Fortifiers Alter the Developing Gastrointestinal Microbiota of Very Low Birth Weight Infants" Read more in @cellhostmicrobe: https://t.co/jvw9fQdXUV @DLOConnor0803 @UofT https://t.co/jvw9fQdXUV - view on twitter