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Keeton, Richardson, Moyo-Gwete et al show that SARS-CoV-2 infection prior to Ad26CoV2.S vaccination significantly boosts cross-reactive ADCC, binding and neutralizing antibodies, and moderately boosts...

Prophages can encode abortive infection proteins that give their bacterial hosts population-level phage defense. Owen et al. show that some of these proteins contain internal...

Li and Hang et al. identify a biosynthetic pathway by which abundant human gut bacterial species from the phylum Bacteroidetes convert the secondary bile acid...

Zabaleta and colleagues report AAVCOVID, an experimental preventative vaccine for COVID-19. AAVCOVID is a vaccine that delivers the SARS-CoV-2 Spike antigen as a gene...

Using a mouse model in which early-life antibiotics enhance T1D, Zhang et al. show that subsequent maternal cecal microbiota transfer reduces illness. The restorative effects...

Rajashekar et al. show that a small molecule CD4 mimetic, in concert with non-neutralizing antibodies, decreases the size of HIV-1 reservoir in new generation humanized...

Mashup Score:318

Cell Host & Microbe

SnapShot: SARS-CoV-2 antibodies - 3 months

Mashup Score:318

Monoclonal antibody therapies hold great promise for COVID-19; however, the recent emergence and spread of escape variants threaten to limit their value. Shown here...

Mankind is currently struggling with two pandemics driven by RNA viruses, HIV-1 and SARS-CoV-2. Here we compare how evolutionary strategies for diversification manifest in...

Motozono and G2P-Japan Consortium et al. show that the emerging mutations L452R and Y453F in the SARS-CoV-2 spike receptor-binding motif evade HLA-A24-restricted cellular immunity. L452R...

CD4 T cell function at the site of infection is crucial to control Mycobacterium tuberculosis. Gern, Adams et al. show that TGFβ inhibits CD4 T cell function...