Canadian Journal of Cardiology Sex-Based Differences in Heart Failure: Pathophysiology, Risk Factors, Management, and Outcomes
Heart failure (HF) is a leading cause of hospitalization and mortality in Canada. There are sex-specific differences in the etiology, epidemiology, and treatment response that have implications on the clinical care and disease trajectory of HF. The under-representation of females in HF RCTs is a major limitation in assessing the sex-specific efficacy of treatments. This review outlines the…
