The range of clinical responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is extremely broad. Although most patients with coronavirus disease 2019 (COVID-19) present with a mild upper respiratory tract infection and then recover, some infected patients develop pneumonia, acute respiratory distress syndrome, multi-organ failure, and death. Clues to the pathogenesis…
Cardiac sarcoidosis is an infiltrative cardiomyopathy that results from granulomatous inflammation of the myocardium and may present with high-grade conduction disease, ventricular arrhythmias, and r
Environmental toxicants and pollutants are causes of adverse health consequences, including well-established associations between environmental exposures and cardiovascular diseases. Environmental de
BACKGROUND: In the BEST-CLI trial (Best Endovascular Versus Best Surgical Therapy for Patients With Chronic Limb-Threatening Ischemia), a prespecified secondary objective was to assess the…
BACKGROUND: Abdominal aortic aneurysm (AAA) is a severe aortic disease without effective pharmacological approaches. The nuclear hormone receptor LXRα (liver X receptor α), encoded by…
BACKGROUND: Adult mammalian cardiomyocytes have limited proliferative capacity, but in specifically induced contexts they traverse through cell-cycle reentry, offering the potential for heart regener
Correspondence to: Alexander C. Bashore, PhD, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, 630 West 168th St, New York, NY 10032.…
Correspondence to: M. Luisa Iruela-Arispe, PhD, Department of Cell and Development Biology, Feinberg School of Medicine, Northwestern University, 303 E. Superior St SQ 8-522, Chicago,…
Correspondence to: Andrea Bellavia, PhD, TIMI Study Group, Brigham and Women’s Hospital, Department of Medicine, Harvard Medical School, 60 Fenwood Rd, Ste 7022, Boston, MA…
Correspondence to: Mary M. McDermott, MD, Northwestern University Feinberg School of Medicine, 750 N Lake Shore Dr, 10th Floor, Chicago, IL 60611. Email Northwestern University…
A collection of available resources for peer reviewers of American Heart Association journals—and for the peer review community more broadly—drawn from research and interviews with…
