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Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Preclinical Cardiotoxicity Screening in Cardio-Oncology:
Highlights •hiPSC-CM offer an alternative to in vivo models for predicting cardiotoxicity.•hiPSC-CM monolayers detect pro-arrhythmic effects; inotropic detection is less established.•Cardiac sphero…
Associations Between Biomarkers of Myocardial Injury and Systemic Inflammation and Risk of Incident Ventricular Arrhythmia:
AbstractBackgroundCardiac troponins (cTns) and biomarkers of inflammation are elevated in heart failure (HF) and predict cardiovascular risk. Whether these biomarkers associate with risk of ventric…
International Clinical Practice Guideline Recommendations for Acute Pulmonary Embolism: Harmony, Dissonance, and Silence
AbstractDespite abundant clinical innovation and burgeoning scientific investigation, pulmonary embolism (PE) has continued to pose a diagnostic and management challenge worldwide. Aging population…
Managing an Advanced Heart Failure Patient at Home With a Long-Term Continuous Intravenous Furosemide Infusion:
AbstractObjectiveTo describe a simple therapeutic intervention for persistent congestion in an advanced heart failure patient using a continuous intravenous furosemide infusion in the home setting…
Managing an Advanced Heart Failure Patient at Home With a Long-Term Continuous Intravenous Furosemide Infusion:
AbstractObjectiveTo describe a simple therapeutic intervention for persistent congestion in an advanced heart failure patient using a continuous intravenous furosemide infusion in the home setting…
Trends in Glucagon-Like Peptide-1 Receptor Agonist Social Media Posts Using Artificial Intelligence:
AbstractBackgroundGlucagon-like peptide-1 receptor agonists (GLP-1RAs) have surged in popularity in recent years, with discussions about their on-label and off-label use spilling into the public fo…
TRIVALVE Score: A Risk Score for Mortality/Hospitalization Prediction in Patients Undergoing Transcatheter Tricuspid Valve Intervention
AbstractBackgroundTranscatheter tricuspid valve intervention (TTVI) has been increasingly adopted in recent years for the treatment of patients with tricuspid regurgitation (TR). However, no dedica…
Acute Heart Failure With Unilateral Pulmonary Edema Due to Aortic Insufficiency During LVAD Support:
AbstractUnilateral pulmonary edema (UPE) is a rare manifestation of cardiogenic pulmonary edema that is often confused with other causes of unilateral pulmonary infiltrates. A 47-year-old…
Embracing Change: Human-Centered Cardiovascular Medicine in the Era of AI
Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, South Korea Institution for Innovation in Digital Healthcare, Yonsei University, Seoul, South Korea ∗Address…
Diversity in Acute Autoimmune Pericarditis: Nationwide Analysis of In-Hospital Outcomes and Recurrence
AbstractBackgroundAcute autoimmune pericarditis (AAP) is an uncommon disease with diverse etiology. Data regarding AAP diagnosis and outcomes are scant.ObjectivesThis study sought to describe the d…