, Leslie M. BarnardLeslie M. Barnard King County Emergency Medical Services, Seattle, WA , Catherine R. CountsCatherine R. Counts Department of Emergency Medicine, University of Washington, Seattle, WA; Seattle Fire Department, Seattle, WA , , Peter J. KudenchukPeter J. Kudenchuk King County Emergency Medical Services, Seattle, WA; Division of Cardiology, University of Washington,…
Correspondence to: Khadijah Breathett, MD, MS, Division of Cardiovascular Medicine, Indiana University, 1800 N Capitol Ave, Indianapolis, IN 46202. E-mail: Division of Cardiovascular Medicine, Department…
BACKGROUND: The risk factor (RF) burden, clinical course, and long-term outcome among patients with atrial fibrillation (AF) aged <65 years is unclear. METHODS: Adult (n=67 221;…
BackgroundThe limited ability of enzyme replacement therapy (ERT) in removing globotriaosylceramide from cardiomyocytes is recognized for advanced Fabry disease cardiomyopathy (FDCM). Prehypertroph…
BackgroundPyroptosis executor GsdmD (gasdermin D) promotes atherosclerosis in mice and humans. Disulfiram was recently shown to potently inhibit GsdmD, but the in vivo efficacy and mechanism…
BackgroundWe aimed to evaluate the impact of hypertensive disorders of pregnancy occurrence, recurrence, onset time, and severity on mortality and on a wide range of…
Heart valve replacement has steadily increased over the past decades due to improved surgical mortality, an aging population, and the increasing use of transcatheter valve…
BACKGROUND: While platelets have well-studied hemostatic functions, platelets are immune cells that circulate at the interface between the vascular wall and white blood cells. The…
Correspondence to: Khadijah Breathett, MD, MS, Division of Cardiovascular Medicine, Indiana University, 1800 N Capitol Ave, Indianapolis, IN 46202. E-mail: Division of Cardiovascular Medicine, Department…
BackgroundIn older adults, obstructive sleep apnea (OSA) has been associated with several cardiovascular complications. Whether young patients diagnosed with OSA also are at higher risk…
Correspondence to: Cyndya Shibao, MD, Division of Clinical Pharmacology, Department of Med icine, Vanderbilt University Medical Center, Nashville, TN 3723. Division of Clinical Pharmacology, Department…
