Podcast Extra: Epigenetics
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A scoping review of reporting gaps in FDA-approved AI medical devices
npj Digital Medicine – A scoping review of reporting gaps in FDA-approved AI medical devices
Potentiation of cortico-spinal output via targeted electrical stimulation of the motor thalamus
Nature Communications – Cerebral lesions result in loss of upper-limb motor functions. Here, the authors show that electrical stimulation of the motor thalamus can immediately…
How to win a Nobel prize: what kind of scientist scoops medals?
What subjects have past winners studied? What age were they when they won? Where do they live? Nature crunched the data on every science prizewinner…
How artificial intelligence can help to keep us safe
Nature – Sociologist Gabriele Jacobs believes AI can be a useful tool in public safety, if developed ethically and responsibly.
An open-source framework for end-to-end analysis of electronic health record data
Nature Medicine – Incorporating a series of analytical steps, from data extraction and quality control to the generation of low-dimensional representations and to longitudinal analyses,…
Defining precancer: a grand challenge for the cancer community
Nature Reviews Cancer – In this Expert Recommendation, Faupel-Badger and colleagues present a conceptual framework to define precancer and advance our understanding of the earliest…
RNA-seq and bulk RNA-seq data analysis of cancer-related fibroblasts (CAF) in LUAD to construct a CAF-based risk signature
Scientific Reports – RNA-seq and bulk RNA-seq data analysis of cancer-related fibroblasts (CAF) in LUAD to construct a CAF-based risk signature
RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis
Nature – Chromatin-associated retrotransposon RNA 5-methylcytosine can be recognized by the methyl-CpG-binding-domain protein MBD6, which guides deubiquitination of nearby monoubiquitinated Lys119…
Targeting oncogenic MAGEA6 sensitizes triple negative breast cancer to doxorubicin through its autophagy and ferroptosis by stabling AMPKα1
Cell Death Discovery – Targeting oncogenic MAGEA6 sensitizes triple negative breast cancer to doxorubicin through its autophagy and ferroptosis by stabling AMPKα1
Characteristics of blood–brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells
Nature Neuroscience – Comprehensive profiling of a circumventricular organ with leaky blood vessels, and comparison to cortex vasculature reveal that blood–brain barrier heterogeneity…