Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndrome
In patients infected with SARS-CoV-2, T lymphocytes stimulated by fragments of viral proteins contribute to immunity but may also promote the development of “cytokine storm.” Weiskopf et al. studied the emergence of antiviral T cells in the blood of 10 patients with severe COVID-19 requiring ventilator treatment by stimulating blood lymphocytes with pools of peptides based on viral protein…
