The potentiation of T cell–mediated antitumor responses achieved in multiple types of cancer via inhibition of the PD-1 checkpoint pathway has led to suggestions that anti–PD-1 therapy might also boost T cell immunity in chronic infections including tuberculosis. Kauffman et al . examined the effect of anti–PD-1 antibody treatment on the clinical course of Mycobacterium tuberculosis (Mtb)…
Antibiotic-resistant bacteria that lead to surgical site infections in spine surgery originate from the preoperative patient microbiome.
The US National Center for Science and Engineering Statistics (NCSES) regularly conducts national surveys of the US-based PhD- and college-educated populations. These surveys monitor who…
Schemes to use renewable energy to process seawater may be cheaper and easier than air capture
China’s massive wave of urbanization may be threatened by land subsidence. Using a spaceborne synthetic aperture radar interferometry technique, we provided a systematic assessment of…
Fully bioresorbable, passive sensor enables continuous, rapid monitoring of pH for early detection of gastric leakage.
In Fig. 1B of the Report “Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase” (5 October 2001, p. 173), an image of the…
Reduced expression of a platelet protein protects against thrombosis during chronic immobilization
Many plans are in preparation to land robotic missions on the surface of the Moon, which will pave the way to return humans to the…
Division of labor among resident tissue macrophages is vital for proper tissue function during homeostasis.
The giant planets of the Solar System formed on initially compact orbits, which transitioned to the current wider configuration by means of an orbital instability.…
