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The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia
Nature Cancer – Lawson et al. show that genetic inactivation of Phd1 or Phd2 hinders progression of AML and compromises leukemic stem cells. They develop…
Underestimated burden of per- and polyfluoroalkyl substances in global surface waters and groundwaters
Nature Geoscience – A global data analysis suggests that a large fraction of surface waters and groundwaters globally have concentrations of per- and polyfluoroalkyl substances…
Thioredoxin is a metabolic rheostat controlling regulatory B cells
Nature Immunology – Here the authors show a mechanism by which mitochondrial electron transport and ROS contribute to the differentiation and function of regulatory B…
A novel system for non-invasive measurement of blood levels of glucose
Nature Reviews Endocrinology – A novel system for non-invasive measurement of blood levels of glucose
Targeting the incretin system in obesity and type 2 diabetes mellitus
Nature Reviews Endocrinology – This article reviews advances in incretin-based pharmacotherapy, including the latest glucagon-like peptide 1 (GLP1) receptor agonists (GLP1RAs), ‘GLP1…
Neuronal TLR9 signalling crucial for memory formation
Nature Reviews Immunology – Neuronal TLR9 signalling crucial for memory formation
Tumour cell consumption of taurine exhausts CD8+ T cells
Nature Reviews Immunology – Tumour cell consumption of taurine exhausts CD8+ T cells
Bacterial serotonin induces Treg cells in neonates
Nature Reviews Immunology – Bacterial serotonin induces Treg cells in neonates
Resolved magnetohydrodynamic wave lensing in the solar corona
Nature Communications – Magnetohydrodynamic (MHD) waves observed on the Sun help understanding solar plasma and involved processes. Here, the authors show resolved MHD waves in…
AI traces mysterious metastatic cancers to their source
Nature – Algorithm examines images of metastatic cells to identify the location of the primary tumour.
