Neuronal NMDAR-TRPM4 “Death Complex” Disabled by Interface Inhibitors
Alzheimer’s and other forms of neurodegeneration may be prevented by small-molecule drugs of a new class, interface inhibitors that disrupt contact surfaces between receptors
Alzheimer’s and other forms of neurodegeneration may be prevented by small-molecule drugs of a new class, interface inhibitors that disrupt contact surfaces between receptors
In AI-based drug discovery—a field benefiting from a cumulative investment of $60 billion—the leaders are making real progress toward approved therapies.
ISM5411 is designed to directly regulate the intestinal immune microenvironment so that the drug simultaneously reduces the gut inflammation seen in IBD while also promoting…
The company will develop a pipeline of small molecule inhibitors that target a unique lipid-binding pocket on proteins.
ISM5411 is designed to directly regulate the intestinal immune microenvironment so that the drug simultaneously reduces the gut inflammation seen in IBD while also promoting…
A new study reveals different types of cancer have unique molecular “fingerprints” which are detectable in early stages of the disease.
Researchers suggest an application to FDA may be made within the next 12 months, requesting approval to carry out a human clinical trial with the…
A single mutation in the surface protein of the highly pathogenic avian influenza (HPAI) H5N1 influenza virus could allow for easier human transmission.
A new study may reshape our understanding of blood flow regulation in the brain.
Kraig Biocraft Laboratories has developed transgenic silkworms to produce spider silk in commercial quantities.
Research shows that GBM organoids are a powerful, accurate tool for understanding what happens when treating a brain tumor using CAR-T cell therapy.