Multiple Sclerosis Provoked by DNA Traps That Promote Immune Cell Specialization

Increase in the levels of NETs—neutrophil extracellular traps, web like structures made of DNA and histones that trap pathogens—have been linked to autoimmune diseases. In a new study, scientists show NETs, through their histones, activate T cells and enhance Th17 cell differentiation. The innate stimulation of a specific adaptive immune cell subset provides a mechanistic link among neutrophils,…

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