Motor neuron-derived microRNAs cause astrocyte dysfunction in amyotrophic lateral sclerosis – PubMed

We recently demonstrated that microRNA-218 (miR-218) is greatly enriched in motor neurons and is released extracellularly in amyotrophic lateral sclerosis model rats. To determine if the released, motor neuron-derived miR-218 may have a functional role in amyotrophic lateral sclerosis, we examined t …

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