Metastasis requires cancer cells to undergo metabolic changes that are poorly understood1–3. Here we show that metabolic differences among melanoma cells confer differences in metastatic potential as a result of differences in the function of the MCT1 transporter. In vivo isotope tracing analysis in patient-derived xenografts revealed differences in nutrient handling between efficiently and…
Nature – Real-time imaging shows how plastic-stuffed cells form clumps that affect mouse movement.
Nature – At-home DNA testing is no longer in high demand — and critics have raised concerns about unreliable tests and privacy.
Nature Medicine – In the TRACERx cohort of 171 patients with lung cancer, the ultrasensitive detection of ctDNA improves preoperative patient stratification, also in early-stage…
Nature Communications – Prediabetics have an increased risk of type 2 diabetes. In this parallel-design, randomized controlled trial, the authors show improvements in metabolic health…
Nature Biotechnology – Liver-avoiding capsids draw $1.1 billion
Nature Medicine – Announced in this Comment and in collaboration with Nature Medicine is the convening of the Quality Health Information for All Commission, to…
Nature Reviews Cardiology – In this Review, Wu and colleagues discuss the evolution in cannabis regulation, the endocannabinoid system and cannabinoid receptors, the influence of…
Nature Communications – The rise in battery production faces challenges from manufacturing complexity and sensitivity, causing safety and reliability issues. This Perspective discusses the…
Nature Medicine – An atlas of the associations between the use of GLP-1 receptor agonists (GLP-1RAs) and 175 health outcomes reports the effectiveness and risks…
Nature Communications – This paper presents a label-free chemoproteomics platform using data-independent acquisition to profile covalent fragment binding across the human proteome. The platform…
