Meta-Research: A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals

An analysis of more than 3000 randomized controlled trials published in JAMA, the Lancet and NEJM has identified 396 medical reversals.

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Source: eLife
Categories: Hem/Oncs
Tweets with this article
Vinay Prasad 2.0
Reading the supplement of the @eLife paper is the medical history that doesn't make the textbooks The missteps of our profession https://t.co/6OrBZKgn4z It's a 400 page antidote to hubris We were honored to have @drjohnm give us his thoughts on it https://t.co/imd6TqKKM8 https://t.co/ij1MIw6tUo
Vinay Prasad 2.0
The history of medicine is littered with early adoption promulgated by charismatic proponents based on lousy data. Costing society and patients billions and billions @adamcifu https://t.co/6OrBZKgn4z https://t.co/fGIbFhcWXn https://t.co/mD3HB4fYUY
Vinay Prasad 2.0
These 396 practices detailed in the appendix are not just practices that were improved upon, or low value, but ones that offer no net benefit, should never have existed, and are NO VALUE. https://t.co/6OrBZKgn4z https://t.co/lcclWNHIBG https://t.co/XCWWDhPZJD
Vinay Prasad 2.0
#2 Two years & 7000 person hours by us Funded by @Arnold_Ventures (without whom, it simply would not have been done) The largest systematic collection of Medical reversals to date in @eLife https://t.co/6OrBZKgn4z https://t.co/8BKTlBcBaB

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