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Mashup Score: 0The Emerging Roles of RNA m6A Methylation and Demethylation as Critical Regulators of Tumorigenesis, Drug Sensitivity, and Resistance - 3 year(s) ago
RNA N6 -methyladenosine (m6A) modification occurs in approximately 25% of mRNAs at the transcriptome-wide level. RNA m6A is regulated by the RNA m6A methyltransferases methyltransferase-like 3 (METTL3), METTL14, and METTL16 (writers), demethylases FTO and ALKBH5 (erasers), and binding proteins YTHDC1–2, YTHDF1–3, IGF2BP1–3, and SND1 (readers). These RNA m6A modification proteins are frequently…
Source: Cancer ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0The emerging roles of RNA m6A methylation and demethylation as critical regulators of tumorigenesis, drug sensitivity, and resistance - 4 year(s) ago
RNA N6-methyladenosine (m6A) modification occurs in approximately 25% of mRNAs at the transcriptome-wide level. RNA m6A is regulated by the RNA m6A methyltransferases METTL3, METTL14, and METTL16 (writers), demethylases FTO and ALKBH5 (erasers), and binding proteins YTHDC1-2, YTHDF1-3, IGF2BP1-3, and SND1 (readers). These RNA m6A modification proteins are frequently upregulated or downregulated…
Source: Cancer ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Lan et al discuss the emerging role of RNA m6A modifying proteins as regulators of tumorigenesis, drug sensitivity and resistance. @JennyYWang2 https://t.co/agGTu9fca3 https://t.co/8sDSgAubBH