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Mashup Score: 5Differential sensing with arrays of de novo designed peptide assemblies - Nature Communications - 2 year(s) ago
Differential sensing aims to mimic senses such as taste and smell through the use of synthetic receptors. Here, the authors show that arrays of de novo designed peptide assemblies can be used as sensor components to distinguish various analytes and complex mixtures.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 6Quantifying and comparing radiation damage in the Protein Data Bank - Nature Communications - 3 year(s) ago
Radiation damage hampers protein structure determination by X-ray crystallography. Here, the AUs introduce the Bnet metric, a single value summarising the extent of radiation damage of a protein crystal structure, and use Bnet to detect radiation damage in structures deposited in the Protein Data Bank.
Source: NatureCategories: General Medicine News, Latest HeadlinesTweet-
A new metric for the extent of radiation damage in protein crystal structures allows analyzing radiation damage in structures deposited in the Protein Data Bank @BristolChem @BristolBiochem @OxBiochNews https://t.co/QNuUtMt93Y https://t.co/T9s9vfsjzh
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Mashup Score: 4
So far most of the de novo designed proteins are for single states only. Here, the authors present the de novo design and crystal structure determination of a coiled-coil peptide that assembles into multiple, distinct conformational states under the same conditions and further characterise its properties with biophysical experiments, NMR and MD simulations.
Source: Nature CommunicationsCategories: General Medicine News, Latest HeadlinesTweet-
New work from Dek Woolfson’s lab: Structural resolution of switchable states of a de novo peptide assembly WoolfsonLab @BristolChem @BrisBioDesign @BristolBiochem @Will_M_Dawson @Eric_jm_lang @Guto_Rhys @AdrianMulholla1 https://t.co/rfnuQmzFqS https://t.co/V4qE694LF2
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Mashup Score: 3
So far most of the de novo designed proteins are for single states only. Here, the authors present the de novo design and crystal structure determination of a coiled-coil peptide that assembles into multiple, distinct conformational states under the same conditions and further characterise its properties with biophysical experiments, NMR and MD simulations.
Source: Nature CommunicationsCategories: General Medicine News, Latest HeadlinesTweet-
New work from Dek Woolfson’s lab: Structural resolution of switchable states of a de novo peptide assembly WoolfsonLab @BristolChem @BrisBioDesign @BristolBiochem @Will_M_Dawson @Eric_jm_lang @Guto_Rhys @AdrianMulholla1 https://t.co/rfnuQmzFqS https://t.co/nej8zuueG2
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Computationally designed de novo peptides provide alternative synthetic receptors for differential sensing. @woolfsonlab, @chriswellswood, @bristolchem, @bristolbiochem, @BrisBioDesign https://t.co/hj7JkTnTYq