AbstractObjectives. The aim of this report is to describe the lung biopsy findings in vaping-associated pulmonary illness.Methods. Lung biopsies from eight pa
Metastatic colorectal cancer with microsatellite instability-high or mismatch repair-deficient status represents a distinct tumour subtype that accounts for around 5% of total colorectal cancer cases.…
Nivolumab plus ipilimumab showed superior progression-free survival versus nivolumab across all treatment lines, with a manageable safety profile, in patients with microsatellite instability-high or mismatch…
T-cell-based immunotherapies have revolutionized cancer treatment, yet only a minority of patients respond to these approaches, significantly constrained by the limited knowledge of tumor-specific antigens.…
Nature Biotechnology – A hybrid model combines quantum and classical approaches to generate compounds targeting the KRAS protein.
Abstract. Pancreatic ductal adenocarcinoma (PDAC) contains an extensive stroma that modulates response to therapy, contributing to the dismal prognosis associated with this cancer. Evidence suggests…
This cohort study investigates the association of adjuvant chemotherapy following resection of pancreatic adenocarcinoma after preoperative FOLFIRINOX in full or modified dosing with overall survival,…
Nature Medicine – An atlas of the associations between the use of GLP-1 receptor agonists (GLP-1RAs) and 175 health outcomes reports the effectiveness and risks…
Nature Medicine – An atlas of the associations between the use of GLP-1 receptor agonists (GLP-1RAs) and 175 health outcomes reports the effectiveness and risks…
Nature Biotechnology – A hybrid model combines quantum and classical approaches to generate compounds targeting the KRAS protein.
Nature Immunology – To mature, dendritic cells collect and synthesize cholesterol to construct lipid nanodomains on their membranes. Obstructing this process impairs their ability to…
