A child growing up today faces an unprecedented threat to their health and livelihood.Our 2019 Lancet Countdown on health and climate change highlighted how the climate emergency is impacting on the health of children right now. Our recent Series on the Double Burden of Malnutrition explored the co-existence of under and over nutrition, and the challenging implications for children in…
Type 2 diabetes has long been thought to have heterogenous causes, even though epidemiological studies uniformly show a tight relationship with overnutrition. The twin cycle…
There was a monotonic relationship between achieved LDL cholesterol and major cardiovascular outcomes down to LDL-cholesterol concentrations of less than 0·2 mmol/L. Conversely, there were…
In this large-scale, nationally representative study, we found consistent inverse associations for most examined serum PFAS compounds in relation to folate concentrations measured in either…
The importance of skeletal muscle mass is increasingly being recognised in the medical field.1 The crucial roles of skeletal muscle have come to the forefront…
Organic male hypogonadism due to irreversible hypothalamic–pituitary–testicular (HPT) pathology is easily diagnosed and treated with testosterone-replacement therapy. However, controversy surrounds the global practice of prescribing…
The prevalence of type 2 diabetes, along with related conditions, such as metabolic syndrome and obesity, has increased globally in the past two decades affecting…
Adults with heterozygous familial hypercholesterolaemia in most WHO regions have a higher type 2 diabetes prevalence than in Europe. Obesity markedly increases the risk of…
Although HbA1c testing remains the gold standard for glucose monitoring in type 1 and type 2 diabetes, limitations include its inability to provide data around…
These CGM data support the long-term efficacy and safety of icodec versus glargine U100 during treatment and indicated no increase in the duration of individual…
These results support larger cross sectional findings indicating that mild Wildtype SARS-CoV-2 infection can be followed by small changes in cognition and memory that persist…
