Hair eruption initiates and commensal skin microbiota aggravate adverse events of anti-EGFR therapy

Therapeutics targeting the epidermal growth factor receptor (EGFR) are used for many cancer types, but they have notable side effects, including a potentially severe and disfiguring skin rash. Klufa et al. discovered that the inhibition of EGFR interferes with the ability of skin stem cells to reestablish a secure barrier after it is broken in the process of hair eruption. This loss of skin…

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