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FDA Approves Lu-177 Dotatate for Pediatric Patients With GEP-NETs
The FDA approved lutetium Lu-177 dotatate (Lutathera) for pediatric patients aged 12 years and older with somatostatin receptor–positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs)—includi…
FDA Grants Accelerated Approval to Tovorafenib for Patients With Relapsed or Refractory BRAF-Altered Pediatric Low-Grade Glioma
On April 23, the FDA granted accelerated approval to the type II RAF inhibitor tovorafenib (Ojemda) for patients 6 months of age and older with…
Wendy Vogel, MSN, FNP, AOCNP, FAPO, on the Evolving Role of Advanced Practice Providers in Oncology Care
Wendy Vogel, MSN, FNP, AOCNP, FAPO, of the Advanced Practitioner Society for Hematology and Oncology, summarizes a panel discussion in which she took part, on…
Induction and Concurrent Vismodegib With Radiation Therapy for Locally Advanced Unresectable Basal Cell Carcinoma
In a phase II study reported in the Journal of Clinical Oncology, Barker et al found that induction treatment with vismodegib followed by concurrent treatment…
Cabozantinib in Metastatic Pheochromocytomas or Paragangliomas
In the single-center phase II Natalie trial reported in The Lancet Oncology, investigators assessed the activity of cabozantinib in patients with unresectable and progressive metastatic…
FDA Approves Nogapendekin Alfa Inbakicept-pmln for BCG-Unresponsive Non–Muscle Invasive Bladder Cancer
On April 22, the U.S. Food and Drug Administration (FDA) approved nogapendekin alfa inbakicept-pmln (Anktiva) with bacillus Calmette-Guérin (BCG) for adults with BCG-unresponsive non–muscle invasive…
Observing a Healthy Diet May Reduce Risk of Cardiovascular Disease in Breast Cancer Survivors
Investigators have examined whether following certain healthy diets may reduce the risk of cardiovascular disease in female breast cancer survivors.
Propofol-Based Anesthesia May Offer Improved Detection of Serrated Polyps During Colonoscopy
Deeper sedation with the anesthetic drug propofol may improve detection of serrated polyps in patients undergoing colonoscopy to screen for colorectal cancer.
Cabozantinib in Metastatic Pheochromocytomas or Paragangliomas
In the single-center phase II Natalie trial reported in The Lancet Oncology, investigators assessed the activity of cabozantinib in patients with unresectable and progressive metastatic…
Nivolumab With or Without Ipilimumab in Recurrent or Metastatic Cervical Cancer
The phase I/II CheckMate 358 trial assessed nivolumab monotherapy and nivolumab/ipilimumab regimens in patients with recurrent or metastatic cervical squamous cell carcinoma. The study findings…