This randomized clinical trial determines whether flecainide dosed to therapeutic levels and added to β-blocker therapy is superior to β-blocker therapy alone for the prevention of exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia.
This Viewpoint addresses the high rate of incorrect ophthalmological diagnoses and harm experienced by patients and examines causes.
This study analyzes data from samples with children 18 years or younger to estimate the average prevalence of adverse childhood experiences, identify characteristics and contexts…
This study describes the characteristics of amyloid-related imaging abnormalities and risk factors and clinical consequences of amyloid-related imaging abnormalities-edema.
This randomized clinical trial evaluates the efficacy and safety of first-line toripalimab vs placebo plus etoposide and platinum-based chemotherapy for treating patients with extensive-stage small…
This cohort study among children and caregiver dyads participating in the Adolescent Brain Cognitive Development Study characterizes unique components of commonly co-occurring traumatic and adverse…
This cohort study evaluates the early uptake of doxycycline postexposure prophylaxis (doxyPEP) and changes in sexually transmitted infection incidence following doxyPEP initiation.
Pressure injuries have long been linked to quality of care. To promote preventive measures and careful ongoing monitoring, the Centers for Medicare & Medicaid Services…
This decision analytical modeling study estimates the burden of metabolic dysfunction–associated steatotic liver disease among US adults from 2020 to 2050.
This survey study examines changes in US adults’ trust in physicians and hospitals over the course of the COVID-19 pandemic and the association between this…
This survey study compares employment decisions among caregivers of preterm infants during the first 3 years of an infant’s life by gestational age and birth…
