Rheumatoid arthritis is multifactorial and is the most common chronic inflammatory rheumatic disease. In many patients, two elements are central in the development of rheumatoid arthritis: autoantibodies directed against citrulline residues (anti-citrullinated peptide antibodies [ACPAs]),1 which can be detected in serum up to 15 years before the onset of clinical symptoms; and the presence of…
Summary:. Research on precancers, as defined as at-risk tissues and early lesions, is of high significance given the effectiveness of early intervention. We discuss the…
Summary:. Research on precancers, as defined as at-risk tissues and early lesions, is of high significance given the effectiveness of early intervention. We discuss the…
Objectives To examine how the lifetime risks of atrial fibrillation and of complications after atrial fibrillation changed over time. Design Danish, nationwide, population based cohort…
Objectives To examine how the lifetime risks of atrial fibrillation and of complications after atrial fibrillation changed over time. Design Danish, nationwide, population based cohort…
Author summary Large language models (LLMs) are the most sophisticated form of language-based artificial intelligence. LLMs have the potential to improve healthcare, and experiments and…
Obesity and type 2 diabetes are prevalent in patients with heart failure with preserved ejection fraction and are characterized by a high symptom burden. No…
The Lancet Breast Cancer Commission—a diverse, multidisciplinary international group—are unanimous in our determination to improve the lives of all people who live with or are…
Patients hospitalized with COVID-19 exhibit age-dependent immune dysregulation at the transcriptional, protein, and cellular levels.
Nature Chemical Biology – Developing disease-modifying drugs for neurodegenerative diseases has been very challenging. Now a machine learning approach has been used to identify small…
The results, while unpublished, are the latest in a string of hopeful signs for weight loss drugs to treat a variety of conditions.
