Explore Tools for COVID-19 Research
Tools to isolate PBMCs, plasma, and viruses.
Tools to isolate PBMCs, plasma, and viruses.
Nature Communications – Co-infections are much less studied than single pathogen infections. Here, the authors show that co-infection with two unrelated viruses, neurotropic Semliki Forest…
Colonic tuft cells can intrinsically resist cytotoxic CD8+ T cells, enabling chronic norovirus infection.
Nature Cell Biology – Duan et al. show that ACE2-dependent and ACE2-independent entry of SARS-COV-2 in epithelial cells versus myeloid cells differentially regulates viral replication…
Signal Transduction and Targeted Therapy – SARS-CoV-2 envelope protein impairs airway epithelial barrier function and exacerbates airway inflammation via increased intracellular Cl−…
Leishmania donovani are intracellular, human blood parasites that cause visceral leishmaniasis or kala-azar. Cell-penetrating peptides (CPPs) have been shown to modulate intracellular processes and cargo…
This study improves our understanding of smallpox vaccination mediated cross-reactivity to orthopox viruses and the durability of childhood smallpox vaccination
BACKGROUND: SARS-CoV-2 infections cause COVID-19 and are associated with inflammation, coagulopathy, and high incidence of thrombosis. Myeloid cells help coordinate the initial immune response in…
Nature Communications – Here the authors describe a stabilization technology that engineers crosslinks between tyrosine sidechains into a natively folded vaccine immunogen and show that…
imageimageA new pipeline for prioritizing protein-protein interactions (PPIs) for drug discovery, combines machine learning-based scoring of quantitative PPI data, protein complex structure prediction and virtual…
Generating an infectious non-human primate (NHP) model using a prevalent monkeypox virus (MPXV) strain has emerged as a crucial strategy for assessing the efficacy of…