Joel Kahn, MD, FACC
Prevention With Joel Kahn, MD
CardiologyDr. Kahn is a summa cum laude graduate of the University of Michigan School of Medicine. He practices cardiology in Detroit, is a clinical professor of medicine at Wayne State University School of Medicine, and specializes in vegan nutrition and heart disease reversal.
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Mashup Score: 0Metformin use and risk of myeloproliferative neoplasms: a Danish population–based case-control study - 1 month(s) ago
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Key Points
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Metformin use was associated with a significant decrease in risk of MPN, with the largest effect observed for the ET and PV subtypes.
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A dose-response relationship supported the association with increasing treatment duration, in particular ≥5 years.
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- For the first time a new study describes the synchronized oscillations during sleep that power the brain’s glymphatic system to help remove ‘waste’ associated with neurodegenerative diseases, via a mouse model.
- Researchers also found that a commonly prescribed sleep aid might suppress those oscillations, disrupting the brain’s waste removal during sleep.
- Looking at all the possible factors that might contribute to potential cognitive decline risk is important, particularly as new research estimates that dementia risk the risk after the age of 55 among Americans has now more than doubled.
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Mashup Score: 0Zero Coronary Artery Calcification: A Promising Value in Acute Chest Pain Evaluation - 1 month(s) ago
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Notably, the absence of CAC (known as CAC Zero) demonstrates exceptional accuracy, including a ~98% negative predictive value for CAD, and predicts excellent short- and intermediate-term prognoses in patients with acute chest pain.
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- Largest meta-analysis to date on statins and dementia risk, including 55 studies and more than 7 million patients.
- Statin use linked to lower risks of all-dementia, AD, and VaD.
- Numerous significant subgroup results highlight statins' diverse neuroprotective effects.
- Findings support statins as a public health tool, especially in low-income countries.
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Mashup Score: 0Individual and additive effects of vitamin D, omega-3 and exercise on DNA methylation clocks of biological aging in older adults from the DO-HEALTH trial - 1 month(s) ago
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In summary, our trial indicates a small protective effect of omega-3 treatment on slowing biological aging over 3 years across several clocks, with an additive protective effect of omega-3, vitamin D and exercise based on PhenoAge.
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Mashup Score: 0New study reveals how a 'non-industrialized' style diet can reduce risk of chronic disease - 1 month(s) ago
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Researchers have found that a newly developed diet inspired by the eating habits of non-industrialized societies can significantly reduce the risk of a number of chronic diseases -- and are to share recipes with the public.
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These findings suggest that short-term juice consumption may negatively affect the microbiota.
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The Metformin and Dietary Restriction to Prevent Age-Related Morbid Events in People With Metabolic Syndrome (MeMeMe) trial tested whether 1,700 mg/day metformin (MET) with or without a Mediterranean diet (MedDiet) intervention could reduce the cumulative incidence of major noncommunicable diseases in people with metabolic syndrome.