Short Diagnosis-to-Treatment Interval Is Associated With Higher Circulating Tumor DNA Levels in Diffuse Large B-Cell Lymphoma

Previous studies had shown short diagnosis to treatment interval (DTI) associated with poor prognosis in DLBCL, which likely contributes to bias in clinical trials. This study shows correlation between elevated ctDNA levels and DTI and that pretreatment ctDNA is associated with other markers of aggressive disease and tumor burden.

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