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In patients with heterozygous familial hypercholesterolemia already taking maximally tolerated lipid-lowering medication, resmetirom lowered LDL, triglycerides, apolipoprotein B and lipoprotein(a) levels vs. placebo, researchers reported.“Heterozygous familial hypercholesterolemia (HeFH) is an autosomal dominant genetic disorder, with an estimated prevalence of approximately one in 200 to