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Oral and Poster Abstracts Oral 627. Aggressive Lymphomas: Clinical and Epidemiological: Treatment of CNS Lymphoma, Neurologic Toxicities, and Relapsed/Refractory DLBCL Research, Biological therapies, adult, Lymphomas, non-Hodgkin lymphoma, Clinical Research, B Cell lymphoma, Chimeric Antigen Receptor (CAR)-T Cell Therapies, Diseases, real-world evidence, aggressive lymphoma,...

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    This retrospective analysis of Relapsed Refractory DLBCL and HGBCL patients showed that patients with relapsed Double Hit lymphoma (DHL, n=80) has similar outcomes post CAR-T then non-DHL patients (n=328). However, outcomes were dismal in DHL after CAR-T failure.