Paper: Cardiac Events in Patients with Acute Myeloid Leukemia Treated with Venetoclax in Combination with Hypomethylating Agents

In a review of 170 AML patients treated at Mayo Clinic with HMA/VEN 20%(!) had a cardiac event, the majority occurred during cycle 1. The most common event was a decrease in the left ventricular ejection fraction. As HMA/VEN use continues to increase in popularity it will be important to keep an eye out for cardiac toxicity.

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