Endpoints used in phase III randomized controlled trials of treatment options for COVID-19

Studies to identify potential drugs effective in treating the coronavirus disease 2019 (COVID-19) are currently ongoing at a rapid pace, although no drug has yet shown improved mortality outcomes in a randomized clinical trial (RCT). Whether the ongoing RCTs are using endpoints that matter remains unknown. Here we provide a summary of the endpoints used in the actively recruiting phase III RCTs…

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