Early testing of convalescent plasma: ‘building the plane while flying it’
Getting an expanded access protocol for convalescent plasma off the ground and testing it as a Covid-19 therapy was a wild ride.
Getting an expanded access protocol for convalescent plasma off the ground and testing it as a Covid-19 therapy was a wild ride.
Suresh Ramalingam Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute Suresh Ramalingam, Terufumi Kato, Xiaorong Dong, Myung-Ju Ahn, Le-Van…
Joseph Greer Massachusetts General Hospital, Harvard Medical School Joseph Greer, Chardria Trotter, Vicki Jackson, Simone Rinaldi, Mihir Kamdar, Areej El-Jawahri, Nora Horick, Kedie Pintro, Dustin…
In an effort to ensure that oncology professionals are providing the highest-quality care, ASCO strives to offer resources and forums to discuss the best
Christian Blank Netherlands Cancer Institute (NKI-AVL), Department of Medical Oncology Christian Blank, Minke Lucas, Richard Scolyer, Bart van de Wiel, Alexander Menzies, Marta Lopez-Yurda, Alexander…
Jens Hoeppner, Thomas Brunner, Florian Lordick, Claudia Schmoor, Birte Kulemann, Ulf Peter Neumann, Gunnar Folprech t, Tobias Keck, Frank Benedix, Maximilan Schmeding, Ernst Reitsamer, Christiane…
Key Points. RAS/RAF mutations are present in up to 61% of patients with multiple myelomaMost of them are subclonal, in agreement with a secondary event
PURPOSE Promising single-agent activity from sotorasib and adagrasib in KRASG12C-mutant tumors has provided clinical evidence of effective KRAS signaling inhibition. However, comprehensive analysis of KRAS-variant…
Background Oncogenic BRAF mutations can be categorized into three classes (I, II and III) based on their distinct structural and signaling properties. BRAF inhibitors are…
PURPOSE An ASCO provisional clinical opinion offers timely clinical direction to ASCO’s membership following publication or presentation of potentially practice-changing data from major studies. This…
npj Precision Oncology – Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA