Repurposing drugs as treatments for COVID-19 has drawn much attention. Beginning with sigma receptor ligands, and expanding to other drugs from screening in the field, we became concerned that phospholipidosis was a shared mechanism underlying the antiviral activity of many repurposed drugs. For all of the 23 cationic amphiphilic drugs tested, including hydroxychloroquine, azithromycin,…
Ability may be widespread in animal kingdom
Much is being made about the erosion of public trust in science. Surveys show a modest decline in the United States from a very high…
The radical new machine might be built faster and cost less than an equivalent conventional atom smasher, boosters say
Macrophages are functionally heterogeneous cells essential for apoptotic cell clearance. Apoptotic cells are defined by homogeneous characteristics, ignoring their original cell lineage identity. We found…
Recent advances on human dendritic cells have opened new avenues to address their subset-specific and cross-lineage programs in cancer.
Eerie rings bigger than galaxies may result from ancient bursts of star formation
A spring-loaded lid that flings insects to their doom has emerged at least twice
Symbiotic interactions were key to the evolution of chloroplast and mitochondria organelles, which mediate carbon and energy metabolism in eukaryotes. Biological nitrogen fixation, the reduction…
Blocking lipid synthesis induces DNA damage in prostate cancer and increases cell death caused by PARP inhibition.
A key mentor ’helped me see that engaging with the people around me would improve my state of mind,“ this researcher writes
